Bone 36 (2005) S103 â S479 www.elsevier.com/locate/bone Abstracts IBMS-ECTS 2005 Abstractsi I001 The Assessment of Fracture Risk: A Global Perspective C. E. De Laet 1 1 Epidemiology Unit, Scientific Institute of Public Health, Brussels, Belgium For many years, the assessment of fracture risk and osteoporosis has been considered almost synonymous with bone mineral density (BMD) measurement. Indeed, diagnostic criteria for osteoporosis, based on absolute or relative BMD, were in practice often used as therapeutic thresholds. Whereas this had the merit of simplicity, we have now more knowledge about other risk factors associated with fracture risk and how these can be incorporated into an overall assessment of fracture risk. When integrating risk factors, one has first to consider the expression of risk. A single and easy to use metric is useful. The T score has served this purpose in the past, but there is a growing consensus that the assessment should concentrate on fracture risk rather than on a biological variable, a similar evolution as, for example, in the field of cardiology, where CVD risk is the outcome of interest rather than blood pressure, although it remains an important intermediate. Fracture risk can be expressed as a risk relative
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