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lipotoxicity, by targeting the primary step in the fatty acid metabolism pathway. Metabolism , Energy, Fatty acid , Hypoxia , Glucose 1. Introduction To power contraction the heart requires a constant supply of ATP ...
oxidative metabolism along with uncoupled respiration. In addition, presence of MB in BAT also influences the free fatty acids pool towards a palmitate-enriched composition and shifts the lipid droplet (LD ...
tolerance. Targeted quantitative metabolic profiling revealed oxylipin-dependent alterations in selected primary metabolites, and glycolytic and citric acid cycle intermediates, as well as a prominent shift ...
), and abscisic acid (ABA), play key roles in plant responses to hypoxia and reoxygenation (Voesenek et al., 2003; Tsai et al., 2014; Chen et al., 2015). To investigate the exact mechanisms by which phytohormones ...
) the levels of miRNAs were slightly altered , and (3) the concentration of LPCs containing unsaturated fatty acids increased following hypoxia . The results of our protein analysis were largely different from ...
membrane, and apoplast (Mignolet-Spruyt et al., 2016). Peroxisomes are the site of several oxidative metabolic processes that can generate ROS, such as β-oxidation of fatty acids and photorespiration (Del ...
. Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart . Cardiovasc Res 72 : 430 – 437 , 2006 . OpenUrl Abstract / FREE Full Text 14 ...
caused by overnutrition drawn from animal studies as well as in vitro studies with cultured cells. In this review, metabolic responses to nutrient overload facilitated by excessive fatty acids ...
(Fig. 1). By an allosteric feed-back mechanism, citrate inhibits glucose utilization [8,9]. Glucose becomes the main substrate for oxidative metabolism of the heart when fatty acid levels are low ...
in diabetic nephropathy.10 In liver cells CD36 is involved in fatty acid metabolism ,27 while on platelets it is related to platelet activation.28 In myocardial tissue, CD36 mediates the uptake of long-chain ...
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