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of hepatic injury, plasma fibrinogen, and plasma hyaluronic acid . At 4, 8, 12, or 18 h after treatment with MCT or its vehicle, rats were anesthetized with sodium pentobarbital (50 mg/kg, ip). A midline ...
of the various oxidative pathways within the hepatocyte was logical. Previous studies have found that lidocaine disposition is a highly sensitive indicator of hepatic dysfunction. Specifically , the kinetics ...
hyaluronic acid was measured as a marker of injury to these cells. Treatment of rats with MCT produced a significant increase in the plasma concentration of hyaluronic acid (Fig. 8A), indicating impaired SEC ...
. Evaluation of serum hyaluronic acid level and hyaluronidase activity in acute and chronic hepatitis C . J Int Med Res . 35 : 346 – 352 . Google Scholar Crossref Search ADS PubMed Jokela TA , Kuokkanen J ...
for the prediction of LC progression that not assessed in retrospective study, such as hyaluronic acid , type IV collagen 7s, P-III-NP, and WFA+-M2BP. The results showed that the serum P-III-NP level and MELD score ...
evaluated in terms of positive predictive value (PPV), negative predictive value (NPV), and the Youden index: sensitivity—(1- specificity ). Both these indices and the Makuuchi criteria were compared using ...
that neutrophils become activated and contributes to additional liver damage (Diao et al., 2004). Interestingly, the specific contribution of OPN versus MIP-2 to hepatic neutrophilic inflammation ...
. Cardiovasc. Pharmacol. 30, 124–129. Google Scholar Kobayashi, H., Horikoshi, K., Yamataka, A., Yamataka, T., Okazaki, T., Lane, G. J., and Miyano, T. ( 1999). Hyaluronic acid : A specific prognostic indicator ...
by altered fenestrae and increases in plasma hyaluronic acid (HA) (Deaciuc et al., 1994; Sarphie et al., 1996). Additionally, damage to endothelial cells and early morphological alterations in hepatic ...
curable. In patients with cirrhosis or chronic viral hepatitis monitored in this way, an increasing serum α-fetoprotein (AFP) concentration may provide the first indication of malignancy, prompting ...
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