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Analysis of Mechanisms of Aging George M. Martin and Mitchell S. Turker Department of Pathology, University of Washington, Seattle. T CAN be argued that the biological basis of aging cannot of a sex ...
Great progress has been made recently in identifying the genetic and likely biological mechanisms of aging traits in humans, thanks to the very large UK Biobank cohort of 500,000 persons ...
factors and of posttranslational modifications in the age -dependent decline of physiological functions. We shall present in this review a short but critical analysis of genetic and epigenetic processes ...
on "Model Systems for the Genetic Analysis of Mechanisms of Aging ." He quotes me correctly, that the Journal of Gerontology: Biological Sciences should not be only a "rat and human journal" but should ...
kidney disease. Accurate phenotyping is essential in performing genetic analysis . For kidney aging , this could include both functional and structural changes. Subsequently, this article reviews the studies ...
Aging of biological systems is a complex process that is controlled by both environmental factors and the genetic constitution of the individual. Although the molecular mechanisms have not been ...
mined 917,645 literature abstracts followed by manual curation, and found strong, non-random associations between age -related diseases and aging mechanisms , confirmed by gene set enrichment analysis ...
BackgroundGenetic research on longevity has provided important insights into the mechanism of aging and aging -related diseases. Pinpointing import genetic variants associated with aging could provide ...
Objective: We hypothesize that mechanisms associated with extended reproductive age may overlap with mechanisms for the selection of genetic variants that slow aging and decrease risk for age -related ...
In a short review of the theories or proposed biological mechanisms of ageing it is necessary to be very selective in the ideas which are included or rejected. Although many theories of ageing ...
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