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showing the mitochondrial proteins that changed with age and/or caloric restriction (CR). Proteins from the mitochondria isolated from liver , heart, and skeletal muscle of young rats fed ad libitum (YAL ...
some scholars had reported that 4-NP exposure affected the energy balance system of the liver , their main research subjects were adult rats with higher doses of 4-NP,13,14 far from the realistic human ...
. Significant differences are indicated Figure 2. Open in new tabDownload slide Concentration of protein complexes I and IV in liver mitochondria from ad libitum–fed and protein- restricted rats . Values are means ...
and metabolomics identified proteins and small molecules in liver mitochondria affected by acute Cd exposure, and MetaCore (Thomson Reuters, https://portal.genego.com/) analysis showed that Cd-altered molecules were ...
when food is eaten. Human physiology shows diurnal patterns with respect to energy metabolism that closely align with circadian rhythms. Upon waking, energy metabolism is upregulated, as observed ...
or caloric restriction , and in times of either low or high energy demand, such as during exercise. The liver , adipose tissue, and muscle govern systemic metabolic flexibility and manage nutrient sensing ...
the probability of suffering degenerative diseases (1). Several hypotheses have been enunciated to explain aging, most of them linked to the mitochondria and the dysregulation of the mitochondrial metabolism (2 ...
is responsible for insulin resistance in rat muscle and liver . In addition, Joseph et al110 proposed that protein phosphatase 2A affected the regulation of AMPK activity by dephosphorylating Thr172. Silent mating ...
(Friedman et al., 1986), synergistically increased food intake in rats . Langhans et al. (1985b) reported that a variety of other fuels metabolized in the liver including lactate, pyruvate, and glycerol caused ...
that animals were killed for estimation of serum T3 levels (9). The livers were removed, weighed, and used for isolation of mitochondria . Sham-operated rats in the three groups, obtained after a small midline ...
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