A selection of World Wide Web sites relevant to papers
published in this issue of Current Opinion in Biotechnology.
Department of Research, University Hospital, Hebelstrasse 20,
CH-4031 Basel, Switzerland
Current Opinion in Biotechnology 2001, 12:435
Expression vectors and delivery systems
Welcome to TBASE: the Transgenic/Targeted Mutation
TBASE is maintained by Anna Anagnostopoulos at Jackson
Laboratory, Bar Harbor as part of the Genetic Resources
Program. TBASE organizes the information generated about
targeted mutations and transgenic animals. Information in the
database includes transgenesis and gene targeting protocols,
transgenic core facilities, a list of knockout models, and access
to related websites.
Foreign Protein Production System Using Plant Cell Culture
Masaaki Terashima is an associate professor at the Department
of Chemical Engineering of the Osaka Prefecture University.
This web page outlines his project on the large-scale produc-
tion of α1-antitrypsin by genetically engineered rice cells.
Japanese version available.
Virus Vectors and Gene Therapy
As a lecture note of the virology course given by Alan Cann and
Shaun Heaphy at the University of Leicester, the section on ‘virus,
vectors and gene therapy’ is written by David Peel. It focuses on
the different classes of viruses used as vectors for gene transfer
and gene therapy. Strategies for gene therapy are discussed.
Actinomycetes–Streptomyces Internet Resource Center
This page is maintained by David Sherman at the Biological
Process Technology Institute (University of Minnesota).
Available information includes protocols and descriptions of
vectors. The site also provides access to other websites
relevant to research on actinomycetes.
Interactive Pseudomonas aeruginosa Genome Database
The complete genome sequence of Pseudomonas aeruginosa
strain PAO1 was determined in a collaboration between the
Cystic Fibrosis Foundation, the University of Washington
Genome Center and PathoGenesis Corporation. This database,
hosted and run by the University of Queensland, can be
searched using gene name, protein name and function, peptide
domain from the protein family database Pfam or BLAST search.
Lecture 28: Food Microbiology
This page is an overview of the course given by Marie
Gilles-Gonzalez at the Ohio State University. Sections include
food microbiology and microbial technology of foods. The latter
section provides detailed examples of food processing
Homepage of the Lactic Acid Bacteria Department at the
Biotechnological Institute Denmark
This site from the Biotechnological Institute in Copenhagen is
dedicated to lactic acid bacteria, with particular emphasis on
lactococcus expression systems. Projects of the institute
described on this page include metabolic engineering for the
food industry and the expression of Mycobacterium tuberculo-
sis antigens for vaccination purposes.
Institute of Biotechnology and Advanced Molecular Medicine
The Biotechnology Foundation, a Pennsylvania non-profit
making corporation, is dedicated to the application of the
methods and tools of biotechnology and to the development of
novel delivery systems for drugs and vaccines. This site lists
the advantages of using tobacco and edible plant-derived
vaccines and outlines ongoing projects supported by the
ARS Genome Database Resource
This plant genomics resource is supported by the Agricultural
Research Service of the US Department of Agriculture, and is
maintained in collaboration with Cornell University Theory
Center. It provides access to plant genomes and chromosome
maps, botanical and animal databases, and newsletters and
websites relevant to these topics.
National Center for Genome Resources
The National Center for Genome Resources, in Santa Fe, New
Mexico, aims to develop biological databases and analytical
software tools for use in studies of genomics, biochemical
pathways and gene expression. Research projects include the
Phytophtora Genome Consortium (plant pathogen) and Plant
Research International (plant genomics).
Journal of Food Science
Expression vectors and delivery systems
Sylvie Miot* and Jean-Louis Boulay