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structure or fluidity. We studied the effects of β‐estradiol and three anti‐ oestrogens (tamoxifen, 4‐hydroxytamoxifen and clomiphene) on Ca2+ uptake into sarcoplasmic reticulum (SR) vesicles isolated from ...
-binding, increases actively the sarcoplasmic reticulum Ca2+-uptake, which directly increases relaxation and indirectly increases contractility. Fig. 4 Open in new tabDownload slide The β-adrenergic pathway ...
Scholar Crossref Search ADS PubMed WorldCat [19] Hasenfuss G. Reinecke H. Studer R. et al. Relationship between myocardial function and expression of sarcoplasmic reticulum Ca2+- ATPase in failing and non ...
elevates Ca2+ activator levels and augments Ca2+ flux through intracellular sarcoplasmic reticulum (SR) Ca2+ storage depots and increases Ca2+ transient amplitude and myocyte shortening (29). Ca2+/calmodulin ...
and FGF- 2 -induced cardioprotection. The effects of ischemic preconditioning include activation of G protein coupled receptors as well as tyrosine kinases [55,58]. Cross-talk between FGF- 2 tyrosine kinase ...
, thereby inhibiting apoptosis. RGN regulates [Ca2+]i by regulating the activity of Ca2+ channels, Ca2+- ATPase in mitochondria and endoplasmic reticulum and (Ca2+–Mg2+)- ATPase in the plasma membrane. It can ...
., and Champeil, P. ( 1991). Kinetics of calcium dissociation from its high-affinity transport sites on sarcoplasmic reticulum ATPase . Biochemistry 30, 352–361. Google Scholar Ritskes-Hoitinga, J., and Beynen ...
approach for HF. Istaroxime is a Na-K ATPase (NKA) inhibitor with the property of accelerating Ca2+ re-uptake into sarcoplasmic reticulum (SR) through the SR Ca2+ pump (SERCA) stimulation by displacing ...
primarily. Indeed, the ATP produced by glycolysis is used preferentially by ion pumps, including the Na+/K+ ATPase and the sarcoplasmic reticulum Ca2+- ATPase SERCA2.91,92 Intriguingly, glycolytic ATP ...
confounding effects related to oestrogen cycle. 2.2 Animal surgery Aortocaval fistula (Shunt) surgery was performed as described previously. 2 In brief, mice were anaesthetised using 1.5% isoflurane insufflation ...
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