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. The antinociception of morphine (10 mg/kg, s.c.) was determined alone or in combination with an appropriate dose of ibogaine or noribogaine . Tolerance to morphine developed as a result of morphine pellet implantation ...
opioid substitution therapy (OST). In this randomized, double‐blind, placebo‐controlled single ascending‐dose study, we evaluated the safety, tolerability , and pharmacokinetics of noribogaine in 27 ...
ABSTRACT: The potential for deriving new psychotherapeutic medications from natural sources has led to renewed interest in rain forest plants as a source of lead compounds for the development ...
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