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BackgroundCigarette smoking is the most significant cause of oral cancer progression. Cigarette smoke condensate (CSC) has been shown to induce endoplasmic reticulum (ER) stress. Binding ...
. However, the molecular alterations occurring in oral fibroblasts exposed to tobacco constituents remain to be elucidated. Methods Oral fibroblasts were exposed to cigarette smoke condensate (CSC) and miRNA ...
. More recently, malignant transformation of HPV16-immortalized human endocervical cells by cigarette smoke condensate has been proven (20). The fact that nicotine and tobacco-specific carcinogens have ...
in the ANOVA. We observed that cigarette smoke induced increases in cell proliferation in the terminal bronchioles and large airways but had no effect in alveoli. The results in the large airways and alveoli ...
receptors (34). A CS condensate induced in vitro the activator protein-1 (AP-1)-associated interleukin-8 (IL-8) and vascular endothelial growth factor in oral keratinocyte and laryngeal squamous carcinoma ...
oral cancer ranks eighth position in cancer incidence (1). Oral squamous cell carcinoma (OSCC) constitutes ~96% of all oral malignancies. OSCC is an imperative cause of morbidity and mortality ...
and neck cancer patients in the coming years. Despite this, few studies have focused specifically on the characteristics and treatment of older patients with squamous cell carcinoma of the head and neck ...
June 2006. Patients were eligible for inclusion in this study if they were older than 17 years and were newly diagnosed with a histologically confirmed squamous cell carcinoma of the oral cavity ...
. The inhibited repair of 6-4PPs was also observed in another cell line, squamous cell carcinoma HSC-1 (Figure 2E). Higher concentrations of CSS were needed to obtain the same inhibitory effects observed in HaCaT ...
of cigarette smoke condensate to induce growth of immortalized lung epithelial (BEAS-2B) cells in soft agar. Taken together, these results illustrate the promise associated with the use of flavonoids ...
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