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. Lung growth was substantially rescued by genetically limiting Cdkn1a and Cdkn1b expression in Tbx2-deficient mice, indicating that suppression of these genes is a critical function of Tbx2 in the control ...
upregulated DE genes at each time point (when compared to the zero hour control ) were interrogated for being oncogenes by their presence in the Memorial Sloan Kettering Cancer Center Oncogene set (http ...
to sample from control transfected cells (open bar), set to 1. Figure 5. Open in new tabDownload slide FGF8 is regulated by Dlx5. (A) Relative abundance of FGF8, Pin1 and ΔN-p63 mRNAs in samples from WT (gray ...
and the downstream signaling that results from Amh activity form a pathway. However, the molecular details of this pathway are currently unknown. A set of essential genes for AMH pathway function has been identified ...
, being either unchanged from control (WLS and Wnt8b), or downregulated ( Wnt5a and Wnt9a, S1 Table), but the majority of Wnt genes analyzed showed similar differential expression patterns between ictal ...
pretreated with Control (DMSO, left) or TGFβ R1 inhibitor (A8301, right). Scale bars represent 200 μm. D) Heatmap demonstrating differential gene expression in patient-derived MSCs treated with DMSO or A83-01 ...
into 96-well flat-bottomed low attachment plates, live cells were gated on the basis of side scatter, forward scatter, and propidium iodide exclusion. Flow cytometric gates were set using control cells ...
to regulate specific gene expression, including WNT ligands Wnt4 and Wnt5a , WNT inhibitors such as Wif1, the transcriptional factor Osx, and the matrix metalloproteinase Mmp2. By unknown mechanisms ...
evolution of male genitalia, at least in vertebrates, is the highly conserved set of genes that appear to be expressed during early genital development, including Sonic Hedgehog (Shh), various fibroblast ...
a temperature-sensitive mutation of the simian virus 40 large tumor antigen gene (tsA58) under the control of interferon γ (IFN-γ) which induces the H-2Kb promoter. All the cells of these mice are “immortalized ...
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