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to class III as XIST RNA is lost from the Xi (Fig. 1) [58]. The same X chromosome is inactivated in all cells of a given hIPSC line reflecting the origin from a single somatic cell [58, 59]. These results ...
to insertion and to explore the mechanism(s) ensuring different transposition outcomes in somatic and germinal cells , we constructed a modified Mu1 element, RescueMu. Transgenic maize was generated to exploit ...
are marked with brackets, and P-values are derived from a two-sided Student's t-test. (B) Strategy for inactivation of PARP-1 in DT40UNG−/− cells . Exons are marked as boxes, primers used for constructing ...
, Hulten MA, Keohane AM and Turner BM ( 1997) Different strategies of X - inactivation in germinal and somatic cells : histone H4 underacetylation does not mark the inactive X chromosome in the mouse male ...
by different B cell lineages, and that some clonotypes may reach the memory pool without an extensive mutation and expansion. antibody-forming cells , bone marrow, somatic hypermutation, spleen, VH genes APFC ...
DIOXYGENASE4), a gene conditioning thermoinhibition of seed germination in lettuce. Three constructs, each capable of expressing Cas9 and a single gRNA targeting different sites in LsNCED4, were stably ...
segregate based on the presence of germinal centers, 2) differently regulated transcripts fall into categories related to immune response, cell proliferation and cell communication/movement, 3) signaling ...
are not limited to PGCs. What subsequent molecular events make PGCs different from the surrounding somatic cells ? Using single- cell gene expression profiles of embryonic day 7.5 (E7.5) founder PGCs and screening ...
of somatic mutation in response to vaccination It is possible that the differences in germinal center activity affect overall maturation and somatic mutation within the CSP-specific B cell receptor (BCR ...
Abstract The recent high-profile reports of the derivation of human embryonic stem cells (ESCs) from human blastocysts produced by somatic cell nuclear transfer (SCNT) have highlighted ...
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