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Abstract Epilepsy is a chronic neurological disorder characterized by spontaneous recurrent seizures (SRS) and comorbidities. Kindling through repetitive brief stimulation of a limbic structure ...
stimulation to the corpus callosum on the mean (± SEM) seizure stage over 25 days in male (diamonds) and female (squares) rats. Both sexes showed increases in seizure severity over 25 days of kindling . Figure 2 ...
of steady drug levels in the blood throughout the day over multiple days to ensure that there will be adequate levels in the system at the time the animals may have unpredictable spontaneous seizures . We ...
29 Marseille, France ). Network oscillations in the gamma‐frequency band (40–100 Hz) have a central role in the transition to seizure . Here we analyzed spontaneous ictal‐like events (ILE) at distinct ...
-epileptic brain into a brain displaying spontaneous seizures [32,33]. SE can be induced in rodents by injecting convulsant agents, such as kainic acid or pilocarpine [34,35]. It develops through 3 main phases ...
of brainstem spreading depolarization in SUDEP, we studied the spatiotemporal distribution of spreading depolarization in the context of seizure -related death. Spontaneous and electrically -induced seizures were ...
in this study is that populations of neurons also give rise to spontaneous slow wave discharges. It is of interest to determine if the spontaneous activity will become synchronous across the tissue and develop ...
al., 1997). The kindling of seizures through electrical stimulation of the amygdala also has been proposed to result in a marked increase in gamma-aminobutyric acid (GABA) stimulation to the DRN ...
epilepticus is followed by a latent period characterized by the functional or morphological changes of the hippocampus over several days to weeks, before the onset of spontaneous recurrent seizures . Although ...
3 the maturity of the underlying pro-ictogenic processes. Progressive Shaping of Absence Seizure Electrical Signature: From Oscillation to SW Complex We further characterized the age-dependent changes ...
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