Dr Gomez Pinilla and his colleagues at the Brain Injury Research Center at University of California-Los Angeles (Los Angeles, California) are to be highly commended for their work on the dietary effects and basic biochemical pathways of natural compounds on synaptic plasticity and mental capacity. Our article on natural antiinflammatory agents for pain relief in athletes mirrored many of the observations he makes in this review [1] . Omega-3 fatty acids and in particular, docosahexaenoic (DHA) is now recognized as essential for optimal brain health and function at all ages of life. It is critical in early brain development. Many studies have shown that higher DHA in baby's diets translates into better brain function especially for cognitive and visual processing [2] . Because phospholipids are a major constituent of cellular membranes, it greatly enhances synaptic function and, as shown by Gomez Pinilla, may have a significant role in traumatic brain injuries. It attenuates traumatic damage in animals pretreated and may help with return of function posttraumatically. In fact, in our clinic, we routinely use omega-3 fatty acids in concussed athletes and are currently evaluating its affects.</P>Curcumin is a naturally occurring yellow pigment derived from tumeric ( Curcuma longa
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