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Abstract The chromosomal translocation t (14;18)(q32;q21) is characteristic of follicular lymphoma and a frequent abnormality in other types of non-Hodgkin lymphoma (NHL). In healthy individuals ...
%–90% of cases of follicular lymphoma , 20%–30% of diffuse large B-cell lymphoma , and 5%–10% of other less common subtypes (1,13,15). The t (14;18) joins the BCL2 gene on chromosome 18 ...
, Eisenberg L, et al. Chromosomal analyses of 52 cases of follicular lymphoma with t (14;18), including blastic/blastoid variant . Cancer Genet Cytogenet. 2001 ; 126 : 45 - 51 . Google Scholar Crossref Search ...
+ − 20 79 f − + 21 48 m − − Case No. . Age, y . Sex . Prior Lymphocytic Thyroiditis . Prior Follicular Lymphoma . 1 51 f + − 2 52 f − + 3 89 f − − 4 77 f − + 5 77 f − − 6 64 m − − 7 75 m − − 8 72 f − − 9 ...
NGS subclones 260 Pediatric-type follicular lymphoma IGH monoclonal rearrangement 334 Follicular lymphoma with 1p36 deletion 1p36 deletion Case No. Panel Diagnosis Genetic Findings 022 Splenic diffuse ...
cytogenetic profile. DHFL cases have been treated both as classic follicular lymphoma and high-grade lymphoma with variable clinical results.8- 18 We summarize one case of double-hit and two cases of triple-hit ...
characteristics between cases and controls were equivalent (Table 1). Although the two main NHL subtypes in the parent case –control study comprised diffuse large B-cell lymphoma (32%) and follicular lymphoma (24 ...
to the low incidence of follicular lymphoma . The t (14;18) translocation has been detected cytogenetically in about 90% of follicular lymphomas and 20%–30% of diffuse large cell lymphomas . This translocation ...
(LDH), though these differences were not significant from traditional DLBCLs in two small case -controlled analyses (Table 1) [5, 10, 12, 14 , 15, 17, 18 ]. Most series suggest, however, that T /HRBCL ...
hematopathologists. After independent and blinded review of tissue specimens, a consensus diagnosis was reached for 1,511 NHL cases , 343 Hodgkin’s disease cases , and 14 unclassifiable lymphomas . Confirmed NHL cases ...
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