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well characterized , little is known about PGD2 and bone metabolism. The objectives of this study were to determine if human osteoblasts can produce PGD2, which prostaglandin D2 synthases are implicated ...
circumstances and thereby induce COX‐2 induction and PGE2 production remain unknown. In this study, we used a human osteoblastic cell line (NHOst) to characterize cellular activities, including inositol phosphate ...
viability, fibronetin levels and osteoblastic maturation on smooth surfaces but not on rough samples. The magnetite beads model used in this study is well suited to characterize the response of hMSCs cultured ...
Open in new tabDownload slide Osteoprotegerin (OPG) production in human gingival fibroblasts (HGF) stimulated with PGE2 and agonists of prostaglandin (PGE) receptors (EP1, EP2, EP3 and EP4 agonist ...
Invest 30 : 429 – 437 , 2000 . OpenUrl CrossRef Medline 52. ↵ Katoh H , Watabe A , Sugimoto Y , Ichikawa A , Negishi M . Characterization of the signal transduction of prostaglandin E receptor EP1 subtype ...
, osteoblasts appear to be the direct or primary targets of bone-resorbing stimuli such as PTH, prostaglandins , and 1α,25-dihydroxyvitamin D3 by expressing receptors for these agents [13]. Osteoblasts may provide ...
the activity of VEGF on osteoblastic cells, we analyzed the expression of receptors for VEGF and performed cell proliferation assays with human MSC-derived osteoblastic cells. VEGF expression in osteoblasts ...
- characterized process of osteoblastic differentiation when placed in culture medium supplemented with β-glycerol phosphate and ascorbic acid [7–10]. Fig 1 presents this process tracked using traditional markers ...
chemoattractants, of which further characterization yielded VEGF as a causative for hMSC-directed osteoblast chemotaxis. With respect to the better understanding of potential hMSC-based periodontal regeneration ...
on collagen production, and attempted to modify these effects through treatment with dexamethasone. The effects of radiation on osteoblast transforming growth factor β1(TGF-β1) receptor expression was also ...
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