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and cytosol , Proc. Natl. Acad. Sci. U. S. A. , 2010 , 107 , 10775 – 10782 . Google Scholar Crossref Search ADS PubMed WorldCat C. Chen and B. H. Paw, Cellular and mitochondrial iron homeostasis in vertebrates ...
, 2006 . OpenUrl Abstract / FREE Full Text 29. ↵ Canonne-Hergaux F , Gruenheid S , Ponka P , Gros P . Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border ...
Abstract Cellular iron homeostasis is regulated by post-transcriptional feedback mechanisms, which control the expression of proteins involved in iron uptake, release and storage. Two cytoplasmic ...
steps in the biosynthesis and maturation of mitochondrial , cytosolic and nuclear Fe–S cluster proteins affects overall cellular iron homeostasis and can lead to severe metabolic, systemic, neurological ...
in iron homeostasis , mitochondrial function, carbohydrate metabolism, cellular proliferation, and innate immunity. Pentose phosphate pathway genes phosphogluconate dehydrogenase, transaldolase ...
Abstract The biogenesis of iron –sulfur (Fe–S) proteins in humans is a multistage process occurring in different cellular compartments. The mitochondrial iron –sulfur cluster (ISC) assembly machinery ...
19p13.2 (23). Although work in yeast indicates that these 2 Fdxs exert nonoverlapping activities, with Fdx1 interacting with mitochondrial P450 enzymes and Fdx2 participating in the biogenesis of iron ...
). Thus, Wolbachia may use iron metabolism as a “skeleton key” to gain access to eukaryotic cellular homeostasis , leading to detrimental or beneficial host–symbiont relationships. Although Wolbachia ...
]-bridged Grx3 homodimers are proposed to transport iron from cytosolic pools to iron -dependent enzymes and the mitochondrion, as well as involvement in regulating cellular iron homeostasis by interacting ...
in iron homeostasis It is well established that defects in mitochondrial Fe-S cluster biogenesis or transport induce transcription of the iron regulon [58], [59] and that Fe-S cluster-containing proteins ...
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