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for protein re-engineering [54]. The basic idea of SCA is to identify groups of residues sharing the same modes of covariations, referred to as “sectors” [55]. Residues projecting to a single sector can ...
. The first patients I took on had the autoimmune disease systemic lupus erythematosus (SLE) and lung cancer. But as they could not be cured, I felt I had hit the limits of medicine. My immediate medical care ...
-terminal, DNA-wrapping domain of the GyrA subunit of Escherichia coli gyrase (the ‘CTD’). The addition or removal of select, conserved basic residues markedly impacts both nucleotide-dependent DNA wrapping ...
] and shown that reannealing prevents replication once a limiting strand concentration is reached when reannealing becomes faster than synthesis of new strands. The limiting concentration is very low ...
that contemporary art has expanded the philosophical horizons of philosophers of art, enabling them to see that hitherto uncharted theoretical moves are possible. Limitations of space have led us to focus ...
Abstract Homologous recombination forms and resolves an entangled DNA Holliday Junction (HJ) crucial for achieving genetic reshuffling and genome repair. To maintain genomic integrity, specialized ...
boundary at position Lys-654 (S3 Table). During rigid body model calculation, constraints were applied to limit distances between these components at covalent bonds linking nucleotides or the peptide ...
her basic selection of traits into doubt. The gaps in her analysis matter also because they mark lost opportunities for genealogical inquiry and comparison. For example, when Ben-Ghiat disclaims ...
: PPT PowerPoint slide PNG larger image TIFF original image Fig 1. LuxIR and Lsr QS components and regulatory mechanisms. (A) The LuxIR system involves a positive feedback loop that entangles AHL synthase ...
supercoiling relaxation increases with the number of domains that bind ssDNA primarily with conserved aromatic residues and possibly with assistance from polar/ basic residues. A comparison of bacterial ...
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