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Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulatory transcription factor that plays an important role in the antioxidant response pathway against anticancer drug - induced ...
modulation of antioxidant enzymes and vitamins might account for differences in species susceptibility to PPs. Accordingly, we measured the activities of DT-diaphorase and superoxide dismutase (SOD ...
relationships between antioxidant enzyme activities and psychotic symptoms (CuZn-SOD: r = −.30, P < .01; Mn-SOD: r = .32, P < .01) in patients. Correlations Between Cognitive Functions and BDNF, MDA, and SOD ...
factor (erythroid-derived 2)-like 2 antioxidant response element, octamer, hypoxia inducible factor 1 alpha, farnesoid-X receptor, TCF/beta-catenin, aryl hydrocarbon receptor, activator protein-1, E2F ...
rifampin. Depending on the ligands, RXR may serve as a silent or an active partner of SXR. Additionally, retinoids can increase CYP3A4 enzyme activity in Huh7 cells. To further evaluate the potential drug ...
the expression and activity of several endogenous antioxidant enzymes [2,4]. Vit E also preserved renal function and structure when administered in vivo to CsA-treated rats [1,2,4]. Immortalized renal proximal ...
factor that upon activation induces a wide variety of cytoprotective genes, such as GSH synthesis enzymes , Gsts, and Mrps; all of which play a role in biliary excretion of xenobiotics. Basal bile flow ...
and copper ionophore induced cell death. Our transcriptomic results suggest that cells do not mount a strong antioxidant reaction in response to the copper ionophores. In fact, H2O2 sink enzymes glutathione ...
cardiovascular and microvascular complications of diabetes. Hyperglycemia induced oxidative stress in the pattern of an increase in reactive oxygen/nitrogen species (ROS/RNS) and consumption of antioxidant ...
, showing improvement in the antioxidant enzyme activity with an increase in drug dose. Silymarin treatment enhanced the antioxidant activity compared to toxin only group. Our results show that gallic acid ...
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