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Journals Current Biology Volume 21 Issue 18

Background Establishment and maintenance of epithelial cell polarity is regulated in part by signaling from adhesion receptors. Loss of cell polarity is associated with multiple pathologies including the initiation and progression of various cancers. The β1-integrin adhesion receptor plays a role in the regulation of cell polarity; however, the identity of the signaling pathways that modulate β1-integrin function and connect it to the regulation of polarity pathways remains largely unknown.

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Arg Kinase Regulates Epithelial Cell Polarity by Targeting β1-Integrin and Small GTPase Pathways

Li, Ran; Pendergast, Ann Marie
Current Biology , Volume 21 (18)
Elsevier – Sep 27, 2011

More Info
  • Publisher Cell Press
  • Copyright Copyright © 2011 Elsevier Ltd
  • ISSN 0960-9822
  • D.O.I. 10.1016/j.cub.2011.08.023
  • Publisher site Get PDF  

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