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changes in hippocampus, entorhinal and piriform cortices of aged wild‐type mice are accompanied by abnormal axonal varicosities and altered expression profiles of calcium‐binding proteins in plaque‐dense ...
to develop more selective treatments for cognitive deficits. Nicotinic Acetylcholine Receptors Regulate Cognitive and Cortical Functions Nicotine enhances sensory– cognitive functions via nicotinic ...
Abstract Background The α7 nicotinic acetylcholine receptor increasingly has been implicated in normal brain physiology, as well as in neuropsychiatric disorders. The highly cortical distribution ...
measured using both tritiated acetylcholine and levorotatory tritiated nicotine binding. References 1. Bowen DM, Smith CB, White P, et al: Neurotransmitter- related enzymes and indices of hypoxia in senile ...
. Cognitive decline in aging and in AD has been linked to a decrease in the availability of nicotinic acetylcholine receptors19,20 (nAChRs) and receptor subunits,21,22 and electrophysiological23,24 and animal ...
of cortical neurones to acidic amino acids and acetylcholine . Brain Res 17: 287–296. Google Scholar Cupp CJ, Uemura E ( 1980) Age - related changes in prefrontal cortex of Macaca mulatta: quantitative analysis ...
evidence that sensorimotor segregation and glucose metabolism underlie some age - related changes in cognition . Interventions that stimulate somatosensory networks could be important for treatment of age ...
is well established, including vigilance, attention, and learning and memory.3-7 Yet, the degree to which noradrenergic systems contribute to the cognitive and behavioural changes resulting from ...
BackgroundStress can exacerbate a number of psychiatric disorders, many of which are associated with prefrontal cortical (PFC) cognitive deficits. Biochemical studies demonstrate that mild stress ...
.Crossref 9. London ED, Waller SB. Relationships between choline acetyltransferase and muscarinic binding in aging rodent brain and in Alzheimer's disease . In: Hanin I, ed. Dynamics of Cholinergic Function ...
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