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Scharrcr u. Schubert: Subcutanfett bei Ratten mit hypothalamischer Fettsucht Z. Klin. Chem. Klin. Biochem. 10. Jg. 1972, S. 326--328 Veränderte Fettsäurezusammensetzung des Subcutanfettes bei Ratten mit hypothalamischer Fettsucht Von E. SCHARRER und RENATE SCHUBERT Institute für Tierphysiologie und Ernährungsphysiologie (Vorstände: Prof. DDr. DDr. h. c. J. Brügge mann, Prof. Dr. Dr. J. Tiews) der Universität München (Eingegangen am 28. Februar 1972) Das Fettsäuremuster des Subcutanfettes hypothalamisch fettsüchtiger Ratten wurde untersucht. Im Vergleich zu normalen Kontrollratten wurde bei Ratten mit hypothalamischer Fettsucht eine signifikante Zunahme des Anteils von 16:0-, 16:1- und 18:l-;Fettsäuren, sowie eine signifikante Verringerung des Gehalts an 18:2- und 20:3-Fettsäuren ermittelt. Zehntägiger Futterentzug führte bei den fettsüchtigen Tieren zu keiner Veränderung des Fettsäuremusters. Alterations in the fatty acid composition of subcutaneous fat in rats with hypothalamic obesity The fatty acid composition of the subcutaneous fat was studied in rats with hypothalamic obesity. Compared with normal control rats, the rats with hypothalamic obesity showed a significant increase in the proportion of 16:0, 16:1 und 18:1 fatty acids and a significant decrease in the content of the 18:2 and 20:3 fatty acids. Starvation for ten days caused no change in £he fatty acid pattern of the rats with hypothalamic
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1972
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