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References (31)
-
M. Correia, R. Burk (1978)
Rapid stimulation of hepatic microsomal heme oxygenase in selenium-deficient rats. An effect of phenobarbital.The Journal of biological chemistry, 253 17
-
R. Muller, H. Taguchi, S. Shibahara (1987)
Nucleotide sequence and organization of the rat heme oxygenase gene.The Journal of biological chemistry, 262 14
-
S. Newman, P. Guzelian (1982)
Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes.Proceedings of the National Academy of Sciences of the United States of America, 79 9
-
R. Stocker (1990)
Induction of haem oxygenase as a defence against oxidative stress.Free radical research communications, 9 2
-
D. Barañano, Herman Wolosker, B. Bae, R. Barrow, S. Snyder, C. Ferris (2000)
A Mammalian Iron ATPase Induced by Iron*The Journal of Biological Chemistry, 275
-
K. Hill, Gary McCollum, M. Boeglin, Raymond Burk (1997)
Thioredoxin reductase activity is decreased by selenium deficiency.Biochemical and biophysical research communications, 234 2
-
E. Uthus, K. Yokoi, C. Davis (2002)
Selenium deficiency in Fisher-344 rats decreases plasma and tissue homocysteine concentrations and alters plasma homocysteine and cysteine redox status.The Journal of nutrition, 132 6
-
C. Ferris, S. Jaffrey, A. Sawa, M. Takahashi, S. Brady, R. Barrow, Steven Tysoe, Herman Wolosker, D. Barañano, S. Doré, K. Poss, S. Snyder (1999)
Haem oxygenase-1 prevents cell death by regulating cellular ironNature Cell Biology, 1
-
M. Maines (1997)
The heme oxygenase system: a regulator of second messenger gases.Annual review of pharmacology and toxicology, 37
-
H. Marver (1969)
THE ROLE OF HEME IN THE SYNTHESIS AND REPRESSION OF MICROSOMAL PROTEIN1 -
P. Seglen (1976)
Preparation of isolated rat liver cells.Methods in cell biology, 13
-
M. Correia, R. Burk (1976)
Hepatic heme metabolism in selenium-deficient rats: effect of phenobarbital.Archives of biochemistry and biophysics, 177 2
-
W. McCoubrey, Tian‐Jun Huang, M. Maines (1997)
Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3.European journal of biochemistry, 247 2
-
C. Allan, G. Lacourciere, T. Stadtman (1999)
Responsiveness of selenoproteins to dietary selenium.Annual review of nutrition, 19
-
N. Goda, Kensuke Suzuki, Makoto Naito, Shinji Takeoka, E. Tsuchida, Yuzuru Ishimura, Takuya Tamatani, Makoto Suematsu (1998)
Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.The Journal of clinical investigation, 101 3
-
R. Mckenzie, J. Arthur, G. Beckett (2002)
Selenium and the regulation of cell signaling, growth, and survival: molecular and mechanistic aspects.Antioxidants & redox signaling, 4 2
-
T. Blackwell, Thomas Blackwell, Edsel Holden, B. Christman, J. Christman (1996)
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.Journal of immunology, 157 4
-
Raymond Burk (2002)
Selenium, an antioxidant nutrient.Nutrition in clinical care : an official publication of Tufts University, 5 2
-
B. Brüne, V. Ullrich (1987)
Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.Molecular pharmacology, 32 4
-
M. Correia, R. Schmid (1975)
Effect of cobalt on microsomal cytochrome P-450: differences between liver and intestinal mucosa.Biochemical and biophysical research communications, 65 4
-
M. Rizzardini, Massimo Zappone, P. Villa, P. Gnocchi, M. Sironi, L. Diomede, C. Meazza, M. Monshouwer, L. Cantoni (1998)
Kupffer cell depletion partially prevents hepatic heme oxygenase 1 messenger RNA accumulation in systemic inflammation in mice: Role of interleukin 1βHepatology, 27
-
Jiying Sun, H. Hoshino, K. Takaku, O. Nakajima, A. Muto, Hiroshi Suzuki, S. Tashiro, Satoru Takahashi, S. Shibahara, J. Alam, M. Taketo, Masayuki Yamamoto, K. Igarashi (2002)
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase‐1 geneThe EMBO Journal, 21
-
R. Burk, B. Masters (1975)
Some effects of selenium deficiency on the hepatic microsomal cytochrome P-450 system in the rat.Archives of biochemistry and biophysics, 170 1
-
P. Wiesel, L. Foster, A. Pellacani, M. Layne, C. Hsieh, G. Huggins, P. Strauss, S. yet, M. Perrella (2000)
Thioredoxin Facilitates the Induction of Heme Oxygenase-1 in Response to Inflammatory Mediators*The Journal of Biological Chemistry, 275
-
D. Gius, A. Botero, Sunita Shah, H. Curry (1999)
Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1.Toxicology letters, 106 2-3
-
R. Burk (1987)
Production of selenium deficiency in the rat.Methods in enzymology, 143
-
M. Correia, R. Burk (1983)
Defective utilization of haem in selenium-deficient rat liver.The Biochemical journal, 214 1
-
I. Bauer, G. Wanner, H. Rensing, C. Alte, E. Miescher, Beate Wolf, B. Pannen, M. Clemens, M. Bauer (1998)
Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress‐exposed rat liverHepatology, 27
-
J. Alam, S. Camhi, A. Choi (1995)
Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer (*)The Journal of Biological Chemistry, 270
-
L. Otterbein, F. Bach, J. Alam, M. Soares, Hong-tao Lu, M. Wysk, R. Davis, R. Flavell, A. Choi (2000)
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathwayNature Medicine, 6
-
Nilufar Inamdar, Young Ahn, Jawed Alam (1996)
The heme-responsive element of the mouse heme oxygenase-1 gene is an extended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors.Biochemical and biophysical research communications, 221 3
- Publisher
- de Gruyter
- Copyright
- Copyright © 2003 by the
- ISSN
- 1431-6730
- DOI
- 10.1515/BC.2003.076
- pmid
- 12751798
- Publisher site
- See Article on Publisher Site
Abstract
Abstract Liver heme oxygenase (HO) activity is higher in selenium-deficient rats than in control animals under basal conditions and is further increased in them, but not in controls, by phenobarbital treatment. In the present study we characterized liver HO induction by selenium deficiency using molecular methods. Severe selenium deficiency in rats caused a doubling of liver HO activity without affecting spleen, kidney, brain, or testis HO activities. HO-1 protein and mRNA were increased to accompany the increased HO activity, but HO-2 protein and mRNA were not increased. Fractionation of the liver into hepatocyte and Kupffer cell/endothelial cell fractions revealed that the increased HO activity resides in the hepatocyte fraction. Immunohistochemical localization of HO-1 protein confirms the induction of HO-1 taking place solely in hepatocytes and throughout the liver lobule. Phenobarbital treatment sharply increased HO-1 mRNA and protein expression in selenium-deficient liver and HO activity in hepatocytes, but had no effect in control liver or in the Kupffer cell/endothelial cell fraction of selenium-deficient liver. Electrophoretic mobility shift assays showed increased AP-1 binding activity, suggesting an involvement of this redoxsensitive transcription factor in the induction by phenobarbital of HO-1 in selenium deficiency. We speculate that selenium deficiency affects hepatic antioxidant selenoproteins, resulting in an upregulation of HO-1.
Journal
Biological Chemistry – de Gruyter
Published: Apr 10, 2003