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H. Bergmeyer (2019)
Methods of Enzymatic Analysis
Introduction The proportion of determinations in the clinical chemistry laboratory based on immunochemical methods is continually increasing. Because of the problems associated with radioimmunoassays (special equipment, disposal of waste), the various enzyme-immunoassays are becoming more important. In addition to the rising number of determinations, however, increasingly strict requirements are being placed on the reproducibility of the results in order to meet the increasing demands, for example in following the course of tumours via long-term monitoring with appropriate tumour markers. This makes mechanisation of such procedures necessary. The first step towards a partially mechanized instrument was made with the ES 22 (1). The ES 600 now available is a fully mechanized instrument which meets all requirements. The ES 600 system, the instrument together with the corresponding enzyme-immunoassays, was subjected to a multicentre trial in six laboratories in accordance with the recommendations of the ECCLS (2). The goal of the study was the verification of the function of the instrument by comparison with another mechanized procedure for the performance of EnzymunTest® methods, which has already been investigated against manual techniques. Tab. 1. Specification of the ES 600 Enzyniun-Test® System according to the guide-lines of the IFCC (3, 4). 1. Type
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1988
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