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Introduction Endemic nephropathy is a chronic disease of still insufficiently known aetiology. It has been recorded in some parts of Yugoslavia (the area of Posavina, west of Slavonski Brod, Podrinje, along the rivers Morava J. Clin. Chem, Clin. Biochcm, / VoJ. 21, 1983 / No. 9 and Kohlbara and in the border areas of Kosovo and Macedonia). It has also been recorded in some parts of Bulgarin and Rumania (1). The investigations carried out so far suggest that endemic nephropathy is quite possi- tvorisccc, Radonic, Ceovic and Aleraj: Characteristics of proteinuria in endemic nephropathy bly a primary disease of thc kidney tubules involving secondary reaction of the interstitial tissue. However, specific diagnostic methods, especially for the early stages of endemic nephropathy when proteinuria is still low are not available. The detection of tubular proteinuria in suspect patients and risk groups living in various endemic areas would be diagnostically useful (2). The aim of this vvork was to establish the grade of proteinuria and recognize its characteristics in the population living in the area with proved endemic nephropathy. The data obtained were compared with those obtained in the investigation of the control rural area where no cases of endemic
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1983
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