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A Rapid Assay for the Quantification of Myoglobin: Evaluation and Diagnostic Relevance in the Diagnosis of Acute Myocardial Infarction

A Rapid Assay for the Quantification of Myoglobin: Evaluation and Diagnostic Relevance in the... Introduction Baum et al: Rapid myogiobin assay in the diagnosis of acute myocardial infarotion Tab. l Within-run and between-day imprecision of the turbidimetric determination of myogiobin concentration. Control sample Intra-assay imprecision: Myogiobin, * (§/1) 101.8 Myogiobin, s ^g/l) 3.74 CV (%) 3.69 n 10 Inter-assay imprecision: 98.6 Myogiobin, (^) 2.99 Myogiobin, s 3.03 CV (%) 52 Serum pool i Serum pool II 160.3 2.83 1.76 10 154.5 5.95 3.85 52 Serum pool III 621.4 14 2.25 10 623.4 17.3 2.77 52 Materials and Methods .Refcrence i n d i v i d u a l s and patients Sera vvere obtained from 100 patients vvith elevated creatine kinase levels; reference limits in this laboratory are 80 U/l for male and 70 U/l for female(ll), - 100 apparently healthy persons (50 males and 50 females) to determine the reference interval. - 18 patients with acute myocardial infarction (at admission and at defmite times after onset of ehest pain); acute myocardial infarction was confirmed with typical changes in ECG and courses of creatine kinase and creatine kinase-MB. Furthermore, two plasma samples with K-ethylenediaminetetraacetate (EDTA) and Na-citrate s an anticoagulant were collected from 20 individuals. All specimens were analysed within 24 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Chemistry and Laboratory Medicine de Gruyter

A Rapid Assay for the Quantification of Myoglobin: Evaluation and Diagnostic Relevance in the Diagnosis of Acute Myocardial Infarction

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Publisher
de Gruyter
Copyright
Copyright © 2009 Walter de Gruyter
ISSN
1434-6621
eISSN
1437-4331
DOI
10.1515/cclm.1994.32.11.853
Publisher site
See Article on Publisher Site

Abstract

Introduction Baum et al: Rapid myogiobin assay in the diagnosis of acute myocardial infarotion Tab. l Within-run and between-day imprecision of the turbidimetric determination of myogiobin concentration. Control sample Intra-assay imprecision: Myogiobin, * (§/1) 101.8 Myogiobin, s ^g/l) 3.74 CV (%) 3.69 n 10 Inter-assay imprecision: 98.6 Myogiobin, (^) 2.99 Myogiobin, s 3.03 CV (%) 52 Serum pool i Serum pool II 160.3 2.83 1.76 10 154.5 5.95 3.85 52 Serum pool III 621.4 14 2.25 10 623.4 17.3 2.77 52 Materials and Methods .Refcrence i n d i v i d u a l s and patients Sera vvere obtained from 100 patients vvith elevated creatine kinase levels; reference limits in this laboratory are 80 U/l for male and 70 U/l for female(ll), - 100 apparently healthy persons (50 males and 50 females) to determine the reference interval. - 18 patients with acute myocardial infarction (at admission and at defmite times after onset of ehest pain); acute myocardial infarction was confirmed with typical changes in ECG and courses of creatine kinase and creatine kinase-MB. Furthermore, two plasma samples with K-ethylenediaminetetraacetate (EDTA) and Na-citrate s an anticoagulant were collected from 20 individuals. All specimens were analysed within 24

Journal

Clinical Chemistry and Laboratory Medicinede Gruyter

Published: Jan 1, 1994

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