ProCeim Database The protein sequence database is maintained and distributed by the Protein Identification Resource of the National Biomedical Research Foundation. There are currently thirteen files which make up this database. One file contains a description of the database as it is distributed. A single large file contains all entries in the current database; each entry consists of a protein sequence and ancillary information. Five recently added index files can be used to determine whether a particular amino acid se- quence is included in the database. The other six files contain additional information about the organization and contents of the database. The protein sequence database is updated quarterly. It currently contains more than 3,500 protein sequences, comprising over 809,000 amino acids. Refer to the DECsystem-10 Technical Notes article, "Introduction to the DNA: Area," for further information on these important databases and their use. Book Review: Clinical Information Systems by Bruce I. Blum Springer-Verlag New York Inc. $53.50 Reviewed by: Charles Sneiderman, National Library of Medicine In the introduction to this thoughtfully crafted, carefully researched, and well illustrated monograph, Bruce Blum explains that his intenaed audience includes health care providers, health care administrators, and information systems implementors. The book is based on a course the author taught at the Johns Hopkins University Department of Biomedical Engineering. I t is intended either as a general introduction to clinical information systems (CIS) or as a text in a medical computing class. The book is organized into three major p a r t s . Part I (Background and Introduction) contains chapters reviewing the history of computing and an overview summarizing progress in medical computing applications. Part I I (Computer Systems) contains chapters overviewing hardware and software concepts, programming languages, data bases, data base management systems, and a software engineering approach to systems implementation. P a r t I I I (Clinical Applications) contains chapters overviewing hospita] information systems, ambulatory care systems, medical decision making, and a "case study" of the Johns Hopkins Oncology Clinical Information System. The chapters are replete with we]l illustrated examples of the principles described with evaluative comments by the author and adequate documentation. Clinical Information Systems is readable and requires v i r t u a l l y no background in either computer science or medical informatics. I t is thus an ideal introductory text for clinical personnel, medical administrators, and students of computer science or engineering. I t w i l l be a useful addition to the collection of medical informatics literature.
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