C0mputer A1ded Mea5urement 0f Dru9 1nduced D15a6111ty Mary K. Wa1ker, PhD., R.N0 A550c1ate Ch1ef 0f 5taff f0r Nur51n9 Re5earch U5VA H05p1ta1, H1ne5 1L 60141 8ack9r0und 7he f1e1d 0f p5ych0pharmac0109y exp10re5 the 1nteract10n 0f dru95 w1th 0n901n9 6ehav10r exh161ted 6y an1ma15 and human5. 5c1ent1f1c 1ntere5t 1n the 6ehav10ra1 effect5 0f dru95 15 n0t new (5pra9ue, 1977). F0r decade5, 1nve5t19at0r5 have 5tud1ed whether certa1n dru95 were capa61e 0f 1nf1uenc1n9 0r a1ter1n9 6ehav10r5 a550c1ated w1th d1ver5e act1v1t1e5 5uch a5: 0pen f1e1d te5t5, 5hutt1e 60x av01dance, key peck1n9, and 5w1tch man1pu1at10n a11 a550c1ated w1th 1ever pre551n9. Fre4uent1y, 5uch 5tud1e5 attempted t0 de5cr16e 0r def1ne the effect5 0f dru95 0n 5uch phen0mena a5 1earn1n9, mem0ry, and perf0rmance. At a11 t1me5, the 4ue5t10n param0unt t0 1nve5t19at0r5 1n the f1e1d 1nv01ved the need f0r m0re 5en51t1ve and re11a61e 6ehav10ra1 pr0cedure5 t0 a55e55 the 6ehav10ra1 act10n5 0f dru95. c0ncerned w1th the de5cr1pt10n and ana1y515 0f the 6ehav10ra1 mechan15m5 6y wh1ch dru95 a1ter 6ehav10r. A further exten510n m19ht 6e that 1n 0rder t0 under5tand the way 1n wh1ch dru95 a1ter 6ehav10r, 1t 15 f1r5t nece55ary t0 under5tand the fact0r5 wh1ch c0ntr01 6ehav10r ~ (We155,1975). 7hu5, a de5cr1pt10n 0f the 1nteract10n5 0f dru9(5) and 6ehav10r mu5t 1nc1ude 60th
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