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A857RAC7 MACH1NE M 0 D E L 5 0 F CELL M E 7 A 8 0 L 1 5 M P R 0 F E 5 5 0 R M1KE H 0 L C 0 M 8 E Department 0f C0mputer 5c1ence Un1ver51ty 0f 5heff1e1d 5heff1e1d, UK. 7he pr1nc1p1e ph11050phy f0r th15 w0rk 15 the repre5entat10n 0f 50me a5pect5 0f ce11u1ar meta60115m a5 c0mputat10n 0f 5u1ta61y def1ned data. 7he ma1n 6enef1t 15 the 0pp0rtun1ty t0 make u5e 0f 50me 0f the the0ret1ca1 m0de15 0f 9enera1, c0ncurrent c0mput1n9 5y5tem5 1n the h0pe that : ¢ the c0mputat10na1 m0de15 may en119hten the 610chem1ca1 the0ry; ¢ the ana1y515 0f 5ucce55fu1 para11e1 610chem1ca1 5y5tem5 w111 en119hten the the0ry 0f para11e1 c0mput1n9. An ear1y attempt t0 m0de1 meta6011c pr0ce551n9 wa5 due t0 Kr0hn, Rh0de5 and Lan9er [5] wh0 u5ed f1n1te 5tate aut0mata t0 m0de1 6a51c meta6011c react10n5. 7he1r pr1nc1p1e a1m wa5 t0 ut1115e a mathemat1ca1 the0rem wh1ch de5cr16ed h0w any 5uch mach1ne c0u1d 6e dec0mp05ed 1nt0 a c011ect10n 0f very e1ementary mach1ne5 ( 6a51c re5et mach1ne5 and 51mp1e 9r0up mach1ne5). 7he u5e 0f a c0mputer a190r1thm t0 he1p w1th th15 dec0mp051t10n 0ffered an 0pp0rtun1ty f0r ana1y51n9 pathway5 1n a n0ve1 way and

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Abstract machine models of cell metabolism

Holcombe, Mike
ACM SIGBIO Newsletter , Volume 12 (2)
Association for Computing MachineryJun 1, 1992

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