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Renal Pharmacology

Renal Pharmacology By JACK ORLOFF AND ROBERT W. BERLINER National Heart Institute, National Institutes of Health, Bethesda, Maryland In the preparation of the first review of an annual series, the aut hors have unique opportunity. A consideration of only material published in the last year or two would hardly suffice as an adequate background for the reviews t o follow; it there fore seems essential to include a wider selection of work to define more adequately the present status of the fi eld. At the same time, freed of the necessity of providing a more or less complete bibliography of material related to the assigned subject for the immediately preceding period, the authors have more freedom in the choice of work to be included and in the presentation of selected areas of study. Pharmacological interest in the kidney i s directed largely along t wo l ines -the effect of drugs on the t ransport mechanisms of the renal tubules and the effect of drugs upon the renal circulation and glomerular act ivity. This review will deal primarily with the renal transport mechanisms for electro­ lytes and water and t he action upon them of several groups of diuretics. Limitations http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Pharmacology and Toxicology Annual Reviews

Renal Pharmacology

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Publisher
Annual Reviews
Copyright
Copyright 1961 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0362-1642
eISSN
1545-4304
DOI
10.1146/annurev.pa.01.040161.001443
Publisher site
See Article on Publisher Site

Abstract

By JACK ORLOFF AND ROBERT W. BERLINER National Heart Institute, National Institutes of Health, Bethesda, Maryland In the preparation of the first review of an annual series, the aut hors have unique opportunity. A consideration of only material published in the last year or two would hardly suffice as an adequate background for the reviews t o follow; it there fore seems essential to include a wider selection of work to define more adequately the present status of the fi eld. At the same time, freed of the necessity of providing a more or less complete bibliography of material related to the assigned subject for the immediately preceding period, the authors have more freedom in the choice of work to be included and in the presentation of selected areas of study. Pharmacological interest in the kidney i s directed largely along t wo l ines -the effect of drugs on the t ransport mechanisms of the renal tubules and the effect of drugs upon the renal circulation and glomerular act ivity. This review will deal primarily with the renal transport mechanisms for electro­ lytes and water and t he action upon them of several groups of diuretics. Limitations

Journal

Annual Review of Pharmacology and Toxicology – Annual Reviews

Published: Apr 1, 1961

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