Access the full text.
Sign up today, get DeepDyve free for 14 days.
H. Nakahara, S. Silver, T. Miki, R. Rownd (1979)
Hypersensitivity to Hg2+ and hyperbinding activity associated with cloned fragments of the mercurial resistance operon of plasmid NR1Journal of Bacteriology, 140
Ying Wang, Inga Mahler, Hillel Levinson, Halvorson, Rosenstiel (1987)
Cloning and expression in Escherichia coli of chromosomal mercury resistance genes from a Bacillus spJournal of Bacteriology, 169
L. Barberis-Maino, Brigitte Berger-Bächi, Hans Weber, W. Beck, F. Kayser (1987)
IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris.Gene, 59 1
B. Rosen, U. Weigel, C. Karkaria, P. Gangola (1988)
Molecular characterization of an anion pump. The arsA gene product is an arsenite(antimonate)-stimulated ATPase.The Journal of biological chemistry, 263 7
R. Olafson, S. Loya, R. Sim (1980)
Physiological parameters of prokaryotic metallothionein induction.Biochemical and biophysical research communications, 95 4
S. Silver, T. Misra (1984)
Bacterial transformations of and resistances to heavy metals.Basic life sciences, 28
R. Laddaga, S. Silver (1985)
Cadmium uptake in Escherichia coli K-12Journal of Bacteriology, 162
Paul Jackson, Clifford Unkefer, Jane Doolen, Ken Watt, Nigel Robinson (1987)
Poly(gamma-glutamylcysteinyl)glycine: its role in cadmium resistance in plant cells.Proceedings of the National Academy of Sciences of the United States of America, 84 19
C. Séguin, D. Hamer (1987)
Regulation in vitro of metallothionein gene binding factorsScience, 235
H. Griffin, T. Foster, S. Silver, T. Misra (1987)
Cloning and DNA sequence of the mercuric- and organomercurial-resistance determinants of plasmid pDU1358.Proceedings of the National Academy of Sciences of the United States of America, 84 10
H. Ogawa, C. Tolle, A. Summers (1984)
Physical and genetic map of the organomercury resistance (Omr) and inorganic mercury resistance (Hgr) loci of the IncM plasmid R831b.Gene, 32 3
Fernando CRUZt, J. Grinsted (1982)
Genetic and molecular characterization of Tn21, a multiple resistance transposon from R100.1Journal of Bacteriology, 151
Peter Lund, Nigel Brown (1987)
Role of the merT and merP gene products of transposon Tn501 in the induction and expression of resistance to mercuric ions.Gene, 52 2-3
T. Misra, N. Brown, D. Fritzinger, R. Pridmore, W. Barnes, L. Haberstroh, S. Silver (1984)
Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes.Proceedings of the National Academy of Sciences of the United States of America, 81 19
A. Radford, J. Oliver, W. Kelly, D. Reanney (1981)
Translocatable resistance to mercuric and phenylmercuric ions in soil bacteriaJournal of Bacteriology, 147
P. Lund, S. Ford, N. Brown (1986)
Transcriptional regulation of the mercury-resistance genes of transposon Tn501.Journal of general microbiology, 132 2
M. Walderhaug, D. Dosch, W. Epstein (1987)
Potassium Transport in Bacteria
E. Grill, E. Winnacker, M. Zenk (1987)
Phytochelatins, a class of heavy-metal-binding peptides from plants, are functionally analogous to metallothioneins.Proceedings of the National Academy of Sciences of the United States of America, 84 2
M. Mergeay, D. Nies, H. Schlegel, J. Gerits, P. Charles, F. Gijsegem (1985)
Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metalsJournal of Bacteriology, 162
P. Gros, J. Croop, D. Housman (1986)
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteinsCell, 47
B. Kreutz, F. Götz (1984)
Construction of Staphylococcus plasmid vector pCA43 conferring resistance to chloramphenicol, arsenate, arsenite and antimony.Gene, 31 1-3
T. Misra, N. Brown, L. Haberstroh, A. Schmidt, D. Goddette, S. Silver (1985)
Mercuric reductase structural genes from plasmid R100 and transposon Tn501: functional domains of the enzyme.Gene, 34 2-3
T. Begley, A. Walts, C. Walsh (1986)
Bacterial organomercurial lyase: overproduction, isolation, and characterization.Biochemistry, 25 22
C. Cervantes-Vega, J. Chávez, N. Córdova, P. Mora, J. Velasco (1986)
Resistance to metals by Pseudomonas aeruginosa clinical isolates.Microbios, 48 196-197
Z. Tynecka, Z. Goś, J. Zajac (1981)
Reduced cadmium transport determined by a resistance plasmid in Staphylococcus aureusJournal of Bacteriology, 147
P. Barrineau, P. Gilbert, W. Jackson, C. Jones, A. Summers, S. Wisdom (1984)
The DNA sequence of the mercury resistance operon of the IncFII plasmid NR1.Journal of molecular and applied genetics, 2 6
C. Sensfuss, M. Reh, H. Schlegel (1986)
No correlation exists between the conjugative transfer of the autotrophic character and that of plasmids in Nocardia opaca strains.Journal of general microbiology, 132 4
H. Ohtake, C. Cervantes, S. Silver (1987)
Decreased chromate uptake in Pseudomonas fluorescens carrying a chromate resistance plasmidJournal of Bacteriology, 169
J. Gerlach, J. Endicott, P. Juranka, G. Henderson, F. Sarangi, K. Deuchars, V. Ling (1986)
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistanceNature, 324
W. Jackson, A. Summers (1982)
Biochemical characterization of HgCl2-inducible polypeptides encoded by the mer operon of plasmid R100Journal of Bacteriology, 151
F. Porter, S. Silver, C. Ong, H. Nakahara (1982)
Selection for mercurial resistance in hospital settingsAntimicrobial Agents and Chemotherapy, 22
C. Bender, D. Cooksey (1987)
Molecular cloning of copper resistance genes from Pseudomonas syringae pv. tomatoJournal of Bacteriology, 169
B. Fox, C. Walsh (1982)
Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide.The Journal of biological chemistry, 257 5
John SteffensS, D. Hunt, B. Williams (1986)
Accumulation of non-protein metal-binding polypeptides (gamma-glutamyl-cysteinyl)n-glycine in selected cadmium-resistant tomato cells.The Journal of biological chemistry, 261 30
D. Higham, P. Sadler, M. Scawen (1986)
Gold-resistant bacteria: excretion of a cystine-rich protein by Pseudomonas cepacia induced by an antiarthritic drug.Journal of inorganic biochemistry, 28 2-3
R. Laddaga, R. Bessen, S. Silver (1985)
Cadmium-resistant mutant of Bacillus subtilis 168 with reduced cadmium transportJournal of Bacteriology, 162
B. Rosen (1986)
Recent advances in bacterial ion transport.Annual review of microbiology, 40
N. Bhriain, T. Foster (1986)
Polypeptides specified by the mercuric resistance (mer) operon of plasmid R100.Gene, 42 3
S. Silver (1983)
Bacterial Interactions with Mineral Cations and Anions: Good Ions and Bad
Many bacterial strains contain genetic determinants of resistances to heavy metals such as Hg2+ (and organomercurials), Ag+ , AsOi, AsO�-, Be+ , BO�-, Cd2+ , C02+ , crO�-, Cu2 + , Ni2+ , Pb3+ , Sb2+ , TeO�-, TI+, Zn2+, and undoubtedly others (91, 100, 106). These resistance determinants are often found on plasmids and transposons (94, 100, 106), which facilitates their analysis by molecular genetic techniques. In the frequent absence of any obvious source of direct selection, these resistances occur with surprisingly 0066-4227/88/1001-0717 $02.00 SILVER & MISRA high frequencies. Selective agents in hospitals and other environments are only beginning to be examined. It has been suggested that heavy metal resistances may have been selected in earlier times, and that they are merely carried along today for a free ride with selection for antibiotic resistances. We doubt that there is such a thing as a free ride as far as these determinants are concerned. For example, in Tokyo in the late 1970s both heavy metal resistances and antibiotic resistances were found with high frequencies in Escherichia coli isolated from hospital patients, whereas heavy metal resist ance plasmids without antibiotic resistance determinants were found in E. coli from an
Annual Review of Microbiology – Annual Reviews
Published: Oct 1, 1988
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.