AbstractMontreal, Downloaded from jn.nutrition.org by guest on January 18, 2011 (Received for publication, June 2, 1939) The purpose of this report is to demonstrate a) the effects of different forms of low-calorie upon the metabolism of , b) the -sparing action of between-meal feedings of carbohydrates with low-calorie of the same composition with respect to carbohydrate fat, but different amounts of animal vegetable s. The importance of knowledge of the different factors which may influence the metabolism of with low-calorie is obvious from the importance of in nutrition from the many people who, for different reasons in health in disease, must reduce their intake of food. Low wage incomes obesity are examples in health; diabetes is an example of disease. Haggard Greenberg ('35) have shown that betweenmeal feedings increase the net muscular efficiencyof the human body that the increase is associated with an increase of carbohydrate metabolis The observations in general fitted in with the well-known fact that mechanical work is best done with carbohydrates; it is done less efficiently with fats least efficiently with . This, however, is not the only beneficial effect of between-meal feedings. The latter prevent the stomach from becoming empty an empty E.