-
J.
Savory,
Brian
Hsu,
Ian
Laquian,
W.
Giffin,
T.
Reich,
R.
Hache,
Y.
Lefebvre
(1999)
Discrimination between NL1- and NL2-Mediated Nuclear Localization of the Glucocorticoid Receptor
Molecular and Cellular Biology, 19
-
K.
Zaret,
K.
Yamamoto
(1984)
Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element
Cell, 38
-
W.
Pratt
(1993)
The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.
The Journal of biological chemistry, 268 29
-
M.
Becker,
C.
Baumann,
S.
John,
D.
Walker,
M.
Vigneron,
J.
McNally,
G.
Hager
(2002)
Dynamic behavior of transcription factors on a natural promoter in living cells
EMBO reports, 3
-
K.
Dahlman-Wright,
A.
Wright,
J.
Gustafsson
(1992)
Determinants of high-affinity DNA binding by the glucocorticoid receptor: evaluation of receptor domains outside the DNA-binding domain.
Biochemistry, 31 37
-
T.
Fletcher,
N.
Xiao,
G.
Mautino,
C.
Baumann,
R.
Wolford,
B.
Warren,
G.
Hager
(2002)
ATP-Dependent Mobilization of the Glucocorticoid Receptor during Chromatin Remodeling
Molecular and Cellular Biology, 22
-
S.
Simons,
E.
Thompson
(1981)
Dexamethasone 21-mesylate: an affinity label of glucocorticoid receptors from rat hepatoma tissue culture cells.
Proceedings of the National Academy of Sciences of the United States of America, 78 6
-
C.
Elbi,
D.
Walker,
G.
Romero,
W.
Sullivan,
D.
Toft,
G.
Hager,
D.
DeFranco
(2004)
Molecular chaperones function as steroid receptor nuclear mobility factors.
Proceedings of the National Academy of Sciences of the United States of America, 101 9
-
J.
McNally,
W.
Müller,
D.
Walker,
R.
Wolford,
G.
Hager
(2000)
The glucocorticoid receptor: rapid exchange with regulatory sites in living cells.
Science, 287 5456
-
W.
Pratt,
D.
Toft
(2003)
Regulation of Signaling Protein Function and Trafficking by the hsp90/hsp70-Based Chaperone Machinery 1
Experimental Biology and Medicine, 228
-
S.
Felts,
D.
Toft
(2003)
p23, a simple protein with complex activities
, 8
-
Ellinor
Oxelmark,
R.
Knoblauch,
Suzzette
Arnal,
L.
Su,
M.
Schapira,
M.
Garabedian
(2003)
Genetic Dissection of p23, an Hsp90 Cochaperone, Reveals a Distinct Surface Involved in Estrogen Receptor Signaling*
Journal of Biological Chemistry, 278
-
M.
Schaaf,
J.
Cidlowski
(2003)
Molecular Determinants of Glucocorticoid Receptor Mobility in Living Cells: the Importance of Ligand Affinity
Molecular and Cellular Biology, 23
-
J.
Iñiguez-Lluhí,
David
Lou,
K.
Yamamoto
(1997)
Three Amino Acid Substitutions Selectively Disrupt the Activation but Not the Repression Function of the Glucocorticoid Receptor N Terminus*
The Journal of Biological Chemistry, 272
-
D.
Stavreva,
W.
Müller,
G.
Hager,
Carolyn
Smith,
J.
McNally
(2004)
Rapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes
Molecular and Cellular Biology, 24
-
B.
Freeman,
S.
Felts,
D.
Toft,
K.
Yamamoto
(2000)
The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies.
Genes & development, 14 4
-
T.
Kino,
Szu-Heng
Liou,
E.
Charmandari,
G.
Chrousos
(2004)
Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching (FRAP) Is an Integrated Measure of Receptor Function
Molecular Medicine, 10
-
D.
Szapary,
Min
Xu
(1996)
Induction Properties of a Transiently Transfected Glucocorticoid-responsive Gene Vary with Glucocorticoid Receptor Concentration*
The Journal of Biological Chemistry, 271
-
B.
Deroo,
C.
Rentsch,
Sowmini
Sampath,
J.
Young,
D.
DeFranco,
T.
Archer
(2002)
Proteasomal Inhibition Enhances Glucocorticoid Receptor Transactivation and Alters Its Subnuclear Trafficking
Molecular and Cellular Biology, 22
-
S.
Simons,
J.
Pumphrey,
S.
Rudikoff,
H.
Eisen
(1987)
Identification of cysteine 656 as the amino acid of hepatoma tissue culture cell glucocorticoid receptors that is covalently labeled by dexamethasone 21-mesylate.
The Journal of biological chemistry, 262 20
-
A.
Agresti,
Paola
Scaffidi,
A.
Riva,
V.
Caiolfa,
M.
Bianchi
(2005)
GR and HMGB1 interact only within chromatin and influence each other's residence time.
Molecular cell, 18 1
-
(2007)
THE LIGAND BINDING DOMAIN REGULATES GR DYNAMICS 2451
-
K.
Yamamoto
(1985)
Steroid receptor regulated transcription of specific genes and gene networks.
Annual review of genetics, 19
-
M.
Schaaf,
Laura
Lewis-Tuffin,
J.
Cidlowski
(2005)
Ligand-selective targeting of the glucocorticoid receptor to nuclear subdomains is associated with decreased receptor mobility.
Molecular endocrinology, 19 6
-
B.
Freeman,
K.
Yamamoto
(2002)
Disassembly of Transcriptional Regulatory Complexes by Molecular Chaperones
Science, 296
-
Shawn
Williams,
P.
Sigler
(1998)
Atomic structure of progesterone complexed with its receptor
Nature, 393
-
R.
Phair,
Paola
Scaffidi,
C.
Elbi,
J.
Vecerova,
A.
Dey,
K.
Ozato,
David
Brown,
G.
Hager,
M.
Bustin,
T.
Misteli
(2004)
Global Nature of Dynamic Protein-Chromatin Interactions In Vivo: Three-Dimensional Genome Scanning and Dynamic Interaction Networks of Chromatin Proteins
Molecular and Cellular Biology, 24
-
W.
Pratt,
D.
Toft
(1997)
Steroid receptor interactions with heat shock protein and immunophilin chaperones.
Endocrine reviews, 18 3
-
A.
Reik,
G.
Schütz,
A.
Stewart
(1991)
Glucocorticoids are required for establishment and maintenance of an alteration in chromatin structure: induction leads to a reversible disruption of nucleosomes over an enhancer.
The EMBO Journal, 10
-
G.
Rayasam,
C.
Elbi,
D.
Walker,
R.
Wolford,
T.
Fletcher,
D.
Edwards,
G.
Hager
(2005)
Ligand-Specific Dynamics of the Progesterone Receptor in Living Cells and during Chromatin Remodeling In Vitro
Molecular and Cellular Biology, 25
-
S.
Simons,
F.
Sistare,
P.
Chakraborti
(1989)
Steroid binding activity is retained in a 16-kDa fragment of the steroid binding domain of rat glucocorticoid receptors.
The Journal of biological chemistry, 264 24
-
G.
Hager,
C.
Elbi,
M.
Becker
(2002)
Protein dynamics in the nuclear compartment.
Current opinion in genetics & development, 12 2
-
L.
Dunkerton,
F.
Markland,
Ming
Li
(1982)
Affinity-labelling corticoids I. Synthesis of 21-Chloroprogesterone, Deoxycorticosterone 21-(1-Imidazole) Carboxylate, 21-Deoxy-21-Chloro Dexamethasone, and Dexamethasone 21-Mesylate, 21-Bromoacetate, and 21-Iodoacetate
Steroids, 39
-
C.
Elbi,
D.
Walker,
Marcia
Lewis,
G.
Romero,
W.
Sullivan,
D.
Toft,
G.
Hager,
D.
DeFranco
(2004)
A Novel In Situ Assay for the Identification and Characterization of Soluble Nuclear Mobility Factors
Science's STKE, 2004
-
J.
Liu,
D.
DeFranco
(1999)
Chromatin recycling of glucocorticoid receptors: implications for multiple roles of heat shock protein 90.
Molecular endocrinology, 13 3
-
A.
Nagaich,
D.
Walker,
R.
Wolford,
G.
Hager
(2004)
Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling.
Molecular cell, 14 2
-
P.
Becker,
B.
Gloss,
W.
Schmid,
U.
Strähle,
G.
Schütz
(1986)
In vivo protein–DNA interactions in a glucocorticoid response element require the presence of the hormone
Nature, 324
-
(1997)
ABI 7700 user's bulletin no. 2. Applied Biosystems
-
R.
Bledsoe,
V.
Montana,
T.
Stanley,
C.
Delves,
C.
Apolito,
D.
Mckee,
T.
Consler,
D.
Parks,
E.
Stewart,
T.
Willson,
M.
Lambert,
John
Moore,
K.
Pearce,
H.E.
Xu
(2002)
Crystal Structure of the Glucocorticoid Receptor Ligand Binding Domain Reveals a Novel Mode of Receptor Dimerization and Coactivator Recognition
Cell, 110
-
P.
Godowski,
D.
Picard,
K.
Yamamoto
(1988)
Signal transduction and transcriptional regulation by glucocorticoid receptor-LexA fusion proteins.
Science, 241 4867
-
G.
Wochnik,
Jason
Young,
U.
Schmidt,
F.
Holsboer,
F.
Hartl,
T.
Rein
(2004)
Inhibition of GR‐mediated transcription by p23 requires interaction with Hsp90
FEBS Letters, 560
-
P.
Godowski,
S.
Rusconi,
R.
Miesfeld,
K.
Yamamoto
(1987)
Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement
Nature, 325
-
A.
Munck,
R.
Foley
(1976)
Kinetics of glucocorticoid-receptor complexes in rat thymus cells.
Journal of steroid biochemistry, 7 11-12