Prevalence of Macrolide Resistance Genes in Clinical Isolates of the Streptococcus anginosus(“S. milleri”) Group
AbstractPrevalence of Macrolide Resistance Genes in Clinical Isolates of the Streptococcus anginosus (“ S. milleri ”) Group Jan A. Jacobs 1 , * , Gilles J. van Baar 1 , Nancy H. H. J. London 1 , Jeroen H. T. Tjhie 1 , Leo M. Schouls 2 , and Ellen E. Stobberingh 1 Department of Medical Microbiology, University Hospital Maastricht, Maastricht, 1 and Research Laboratory for Infectious Diseases, National Institute of Public Health and the Environment, 3720 BA Bilthoven, 2 The Netherlands ABSTRACT Twenty-two unrelated erythromycin-resistant anginosus group strains (3.2% resistance rate) were assessed for mechanisms of resistance. Streptococcus anginosus accounted for 16 of the 22 isolates. Fifteen isolates harbored the erm (B) gene. The erm (TR) and the mef (E) genes were carried by two isolates each. In three isolates, none of these resistance genes was detected by PCR.