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Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR N. Fernando 1 , J. Holton 1 , * , D. Vaira 2 , M. DeSilva 3 and D. Fernando 3 1 Department of Bacteriology, Royal Free & University College London Medical School, London, United Kingdom 2 First Medical Clinic, University of Bologna, Bologna, Italy 3 Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardena, Colombo, Sri Lanka ABSTRACT Fifty-seven Sinhalese patients were investigated for the presence of Helicobacter pylori by PCR. A prevalence of 70.1%, with 47.5% positive for cagA , was demonstrated. The most common vacA allele was s1am1. There was no significant association between either the s1 allele or the cagA allele and severe gastroduodenal disease. There was an association between the s1 allele and the cagA locus. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical Microbiology American Society For Microbiology

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR

Journal of Clinical Microbiology , Volume 40 (7): 2675 – Jul 1, 2002

Abstract

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR N. Fernando 1 , J. Holton 1 , * , D. Vaira 2 , M. DeSilva 3 and D. Fernando 3 1 Department of Bacteriology, Royal Free & University College London Medical School, London, United Kingdom 2 First Medical Clinic, University of Bologna, Bologna, Italy 3 Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardena, Colombo, Sri Lanka ABSTRACT Fifty-seven Sinhalese patients were investigated for the presence of Helicobacter pylori by PCR. A prevalence of 70.1%, with 47.5% positive for cagA , was demonstrated. The most common vacA allele was s1am1. There was no significant association between either the s1 allele or the cagA allele and severe gastroduodenal disease. There was an association between the s1 allele and the cagA locus.

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References (11)

Publisher
American Society For Microbiology
Copyright
Copyright © 2002 by the American society for Microbiology.
ISSN
0095-1137
eISSN
1098-660X
DOI
10.1128/JCM.40.7.2675-2676.2002
Publisher site
See Article on Publisher Site

Abstract

Prevalence of Helicobacter pylori in Sri Lanka as Determined by PCR N. Fernando 1 , J. Holton 1 , * , D. Vaira 2 , M. DeSilva 3 and D. Fernando 3 1 Department of Bacteriology, Royal Free & University College London Medical School, London, United Kingdom 2 First Medical Clinic, University of Bologna, Bologna, Italy 3 Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardena, Colombo, Sri Lanka ABSTRACT Fifty-seven Sinhalese patients were investigated for the presence of Helicobacter pylori by PCR. A prevalence of 70.1%, with 47.5% positive for cagA , was demonstrated. The most common vacA allele was s1am1. There was no significant association between either the s1 allele or the cagA allele and severe gastroduodenal disease. There was an association between the s1 allele and the cagA locus.

Journal

Journal of Clinical MicrobiologyAmerican Society For Microbiology

Published: Jul 1, 2002

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