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Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain9V-3 Clone

Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from... Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain 9V -3 Clone C. Ardanuy 1 , * , A. Fenoll 2 , S. Berrón 2 , L. Calatayud 1 , J. Liñares 1 and the Spanish Pneumococcal Infection Study Network † 1 Servicio de Microbiología, Hospital de Bellvitge, Barcelona, Spain 2 CNM Instituto de Salud Carlos III, Madrid, Spain ABSTRACT Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS B phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% ( P < 0.01). Clonal dissemination of mef (E)-carrying strains of serotype 14 variant of the Spain 9V -3 clone was the major contributor to this increase. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Antimicrobial Agents and Chemotherapy American Society For Microbiology

Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain9V-3 Clone

Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain9V-3 Clone

Antimicrobial Agents and Chemotherapy , Volume 50 (9): 3162 – Sep 1, 2006

Abstract

Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain 9V -3 Clone C. Ardanuy 1 , * , A. Fenoll 2 , S. Berrón 2 , L. Calatayud 1 , J. Liñares 1 and the Spanish Pneumococcal Infection Study Network † 1 Servicio de Microbiología, Hospital de Bellvitge, Barcelona, Spain 2 CNM Instituto de Salud Carlos III, Madrid, Spain ABSTRACT Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS B phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% ( P < 0.01). Clonal dissemination of mef (E)-carrying strains of serotype 14 variant of the Spain 9V -3 clone was the major contributor to this increase.

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References (36)

Publisher
American Society For Microbiology
Copyright
Copyright © 2006 by the American society for Microbiology.
ISSN
0066-4804
eISSN
1098-6596
DOI
10.1128/AAC.00269-06
pmid
16940119
Publisher site
See Article on Publisher Site

Abstract

Increase of the M Phenotype among Erythromycin-Resistant Streptococcus pneumoniae Isolates from Spain Related to the Serotype 14 Variant of the Spain 9V -3 Clone C. Ardanuy 1 , * , A. Fenoll 2 , S. Berrón 2 , L. Calatayud 1 , J. Liñares 1 and the Spanish Pneumococcal Infection Study Network † 1 Servicio de Microbiología, Hospital de Bellvitge, Barcelona, Spain 2 CNM Instituto de Salud Carlos III, Madrid, Spain ABSTRACT Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS B phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% ( P < 0.01). Clonal dissemination of mef (E)-carrying strains of serotype 14 variant of the Spain 9V -3 clone was the major contributor to this increase.

Journal

Antimicrobial Agents and ChemotherapyAmerican Society For Microbiology

Published: Sep 1, 2006

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