Identification, characterization, and sequence analysis of a cDNA encoding a phosphoprotein of human herpesvirus 6.
Abstract
CONTENT ALERTS Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» Information about commercial reprint orders: http://jvi.asm.org/site/misc/reprints.xhtml To subscribe to to another ASM Journal go to: http://journals.asm.org/site/subscriptions/ Downloaded from http://jvi.asm.org/ on December 19, 2011 by deepdyve AUTHOR'S CORRECTION CHEOW K. CHANG AND N. BALACHANDRAN Department of Microbiology, Molecular Genetics and Immunology, The University of Kansas Medical Center, Kansas City, Kansas 66103 Volume 65, no. 6, pages 2884-2894: We have reported the identification of a cDNA clone encoding the HHV-6 phosphoprotein P41 and suggested that HHV-6 P41 is encoded within a gene coding for a larger protein. This suggestion was based on the nucleotide sequence of the cDNA insert identified by the MAb 9A5D12, which revealed a 623-amino-acid residue single ORF of 1,871 nucleotides, with an open 5' end. Since then, we have used the cDNA insert to clone the 3.8-kb HHV-6(GS) genomic insert and have sequenced part of the genomic fragment. During comparison with the cDNA sequence, we found an error in our previously reported cDNA sequence. The nucleotides AA should be inserted between positions 1145 and 1146 in the cDNA sequence reported in Fig. 4 of our paper. Insertion of these two nucleotides (AA) results in the following changes in the sequence and in the conclusions. (i) The cDNA clone encodes two ORFs instead of the reported single ORF. The addition of the two AA's shifted the reading frame by the generation of stop codon TGA at nucleotide positions 1165 to 1167 in reading...
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