Free Genome Sequence of the Fungus Glarea lozoyensis : the First Genome Sequence of a Species from the Helotiaceae Family Loubna Youssar a , Björn Andreas Grüning b , Anika Erxleben b , Stefan Günther b and Wolfgang Hüttel a a Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Freiburg, Germany b Institute of Pharmaceutical Sciences, Pharmaceutical Bioinformatics, University of Freiburg, Freiburg, Germany ABSTRACT The anamorphic fungus Glarea lozoyensis mutant strain 74030 is an overproducer of pneumocandin B 0 , which is chemically converted into Cancidas, a potent antibiotic against clinically important fungal pathogens. Pneumocandins are acylated, cyclic hexapeptides with unusual hydroxylated amino acids. With the Glarea lozoyensis genome, the first species from the large polyphyletic family Helotiaceae has been sequenced.
Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family
Abstract
Free Genome Sequence of the Fungus Glarea lozoyensis : the First Genome Sequence of a Species from the Helotiaceae Family Loubna Youssar a , Björn Andreas Grüning b , Anika Erxleben b , Stefan Günther b and Wolfgang Hüttel a a Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Freiburg, Germany b Institute of Pharmaceutical Sciences, Pharmaceutical Bioinformatics, University of Freiburg, Freiburg, Germany ABSTRACT The anamorphic fungus Glarea lozoyensis mutant strain 74030 is an overproducer of pneumocandin B 0 , which is chemically converted into Cancidas, a potent antibiotic against clinically important fungal pathogens. Pneumocandins are acylated, cyclic hexapeptides with unusual hydroxylated amino acids. With the Glarea lozoyensis genome, the first species from the large polyphyletic family Helotiaceae has been sequenced.Preview Only. This article cannot be rented because we do not currently have permission from the publisher.
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Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family
Youssar, Loubna; Grüning, Björn Andreas; Erxleben, Anika; Günther, Stefan; Hüttel, Wolfgang
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, Volume 11 (2): 250
American Society For Microbiology – Feb 1, 2012
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