Demonstration of R Factors in Bordetella bronchiseptica Isolated from Pigs

Demonstration of R Factors in Bordetella bronchiseptica Isolated from Pigs Nobuyuki Terakado , Hayami Azechi , Kiyoji Ninomiya and Takeshi Shimizu The National Veterinary Assay Laboratory, Kokubunji, Tokyo, Japan The National Institute of Animal Health, Kodaira, Tokyo, Japan ABSTRACT Transferability of drug resistance in strains of Bordetella bronchiseptica isolated from pigs was examined. These strains were resistant to sulfadimethoxine (SA, more than 1,600 μg/ml), streptomycin (SM, more than 800 μg/ml), and aminobenzyl penicillin (APC, 200 μg/ml). All of them could transfer their drug resistance as one unit to a sensitive strain of Escherichia coli as well as to B. bronchiseptica by mixed cultivation. The transferred SM-SA-APC resistance in the exconjugants of E. coli and B. bronchiseptica was also transmissible by mixed cultivation. But the transfer of triple resistance was not mediated by the cell-free filtrate of the drug-resistant strain of B. bronchiseptica which was used as donor. The triple resistance in the exconjugant E. coli ML1410 was found to be eliminated as a whole by treatment with acriflavin. According to these results, it could be safely concluded that R factors carrying SM-SA-APC resistance were demonstrated in strains of B. bronchiseptica isolated from pigs. Copyright © 1973 American Society for Microbiology CiteULike Connotea Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter What's this? « Previous | Next Article » Table of Contents This Article doi: 10.1128/​AAC.3.5.555 Antimicrob. Agents Chemother. May 1973 vol. 3 no. 5 555-558 » Abstract PDF Classifications ARTICLE Services Email this article to a colleague Similar articles in ASM journals Alert me when this article is cited Alert me if a correction is posted Similar articles in this journal Similar articles in Web of Science Similar articles in PubMed Alert me to new issues of AAC Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Load citing article information Citing articles via Web of Science Citing articles via Google Scholar Google Scholar Articles by Terakado, N. Articles by Shimizu, T. Search for related content PubMed PubMed citation Articles by Terakado, N. Articles by Shimizu, T. Related Content Load related web page information Social Bookmarking CiteULike Connotea Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter What's this? current issue December 2011, volume 55, issue 12 Alert me to new issues of AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • [email protected] Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2011 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: http://intl- AAC .asm.org | More Info»