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further queried as to concurrent antimicrobial therapy or possible exposure to a case of gonorrhea, diagnosed or suspected. Subsequently they were examined by a physician for the presence of a urethral discharge. On the basis of the interview and physician appraisal, 2,811 were assigned to the study population. Excluded were: 1) all diagnosed as having gonococcal urethritis by microscopic examination of a urethral exudate; 2) patients currently under antimicrobial therapy for syphilis, gonorrhea, or other infection; 3) patients already examined within the study protocol who returned within three days for evaluation of a medical problem other than urethritis or penile exposure to gonorrhea; and 4) patients refusing to have a urethral culture. Diagnostic Technique The study population had urethral cultures taken using urethrogenital calcium alginate swabs which were inoculated upon modified Thayer-Martin plates and incubated in a candle jar at 36°C. The plates were examined for growth after 24 and 48 hours. Positive cultures were identified by colony morphology, positive oxidase reaction, and gram stain performed by a public health microbiologist. Results Results of the cultures of the 2,811 patients, categorized as to history of sexual exposure to gonorrhea, and existence of signs and/or symptoms of urethritis are
American Journal of Public Health – American Public Health Association
Published: Aug 1, 1978
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