Instant Access to the Journals You Need

for just $40 per month.

Neurological and Psychopathological Sequelae Associated With a Lifetime Intake of 40,000 Ecstasy Tablets

Neurological and Psychopathological Sequelae Associated With a Lifetime Intake of 40,000 Ecstasy Tablets

Abstract

TO THE EDITOR: The medical and psychopathological consequences of both acute and chronic "ecstasy" (MDMA, MDA, and derivatives) consumption have been extensively described, but little is known with respect to the relationship between both severity and persistence of these disturbances and lifetime number of ecstasy tablets ingested. At-risk MDMA intake seems to be related to long-term functional dysregulation in 5-HT2 pathways, resulting in altered regulation of mood, impulse control, and memory.1,2 Ecstasy consumption has spread since the late ‘80s, and the reduction in price observed over the last few years has possibly increased access to the drug. Clinicians are now meeting with a generation of patients who have been exposed to the drug for more than a decade. In this report, we describe both the transient and persisting sequelae associated with an unusual amount of ecstasy consumption. Case Report Mr. A, 37 years old, used ecstasy between the ages of 21 and 30. For the first 2 years, he took 5 tablets every weekend, escalating to an average daily use of 3.5 tablets for the next 3 years, and further escalation to an average of 25 tablets daily over the next 4 years. An estimate of lifetime consumption
Loading next page...
 
/lp/american-psychiatric-publishing-inc-journal/neurological-and-psychopathological-sequelae-associated-with-a-mw6Z6vrXxK

You're reading a free preview. Sign up for Instant Access to thousands of journals for just $40/month.

By signing up, you agree to DeepDyve's Terms of Service and Privacy Policy.

What content is in DeepDyve?

  • Read and share from thousands of the leading scholarly journals from Springer, Elsevier, Nature, IEEE, Wiley-Blackwell and more.
  • All the latest content is available, no embargo periods.

Rent Scholarly Articles?

  • Read the full article in your browser.
  • Access all of your rentals from the cloud anywhere you have an internet connection.
  • Beautiful reading experience – Full charts and figures, just like the PDF.
  • Read as much as you'd like - whenever you'd like.

Happy Users

“In one word renting from DeepDyve is FANTASTIC!!! ... 99% of the time I only need access to an article for a month or so, so renting the articles is perfect for me.”

Adam S.

“Thanks for a great service! For an unaffiliated science blogger like myself this is like a dream come true.”

Seppo P.

“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”

Daniel C.

“Let me seize this opportunity and congratulate you on the service you are rendering to the scientific community.”

Joao B.