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Sexual dysfunction is a very common and distressing problem caused by diverse physical, psychological, lifestyle, and medication-related factors. When men and women seek treatment for sexual dysfunction at any age but particularly at midlife and beyond, what medications, hormonal and nutritional factors should the clinician consider and why? When a patient presents with a sexual problem, the clinician first must attempt to determine the specific nature of the problem and its potential cause(s). Is the patient taking any of the numerous medications that may contribute to sexual dysfunction, such as antihypertensives, mood stabilizers, antidepressants, birth control pills, antipsychotics, cytotoxic agents, nonsteroidal anti-inflammatory medications, hormones, and antihistamines? Does the patient have a history of psychiatric illness or any medical conditions that may play a role, including hormonal imbalances and nutritional deficiencies? Below I review some of the evidence for sexual dysfunction related to hormonal and micronutrient deficiencies and discuss the potential relevance of hormone replacement and micronutrient supplementation. Much has been written about the sexual side effects of the widely used selective serotonin reuptake inhibitor (SSRI) antidepressants (1). They cause sexual dysfunction through several mechanisms, including inhibition of cholinergic activity, inhibition of nitric oxide synthetase, reduction of dopaminergic activity,

Ask the Expert: Sexual Dysfunction Medication, Hormones, and Nutrition

Abstract

Sexual dysfunction is a very common and distressing problem caused by diverse physical, psychological, lifestyle, and medication-related factors. When men and women seek treatment for sexual dysfunction at any age but particularly at midlife and beyond, what medications, hormonal and nutritional factors should the clinician consider and why? When a patient presents with a sexual problem, the clinician first must attempt to determine the specific nature of the problem and its potential cause(s). Is the patient taking any of the numerous medications that may contribute to sexual dysfunction, such as antihypertensives, mood stabilizers, antidepressants, birth control pills, antipsychotics, cytotoxic agents, nonsteroidal anti-inflammatory medications, hormones, and antihistamines? Does the patient have a history of psychiatric illness or any medical conditions that may play a role, including hormonal imbalances and nutritional deficiencies? Below I review some of the evidence for sexual dysfunction related to hormonal and micronutrient deficiencies and discuss the potential relevance of hormone replacement and micronutrient supplementation. Much has been written about the sexual side effects of the widely used selective serotonin reuptake inhibitor (SSRI) antidepressants (1). They cause sexual dysfunction through several mechanisms, including inhibition of cholinergic activity, inhibition of nitric oxide synthetase, reduction of dopaminergic activity,

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Ask the Expert: Sexual Dysfunction Medication, Hormones, and Nutrition

Bartlik, Barbara
FOCUS: The Journal of Lifelong Learning in Psychiatry , Volume 8 (4): 547
American Psychiatric Publishing, Inc (Journal) Oct 1, 2010

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  • Publisher Am Psych Publishing
  • Copyright Copyright © 2010 American Psychiatric Association. All rights reserved.
  • ISSN 1541-4094
  • Publisher site Get PDF  

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