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An Immunoelectron Microscopy Study of Soehner-Dmochowski Murine Sarcoma Virus following Passage in Rats and Hamsters

An Immunoelectron Microscopy Study of Soehner-Dmochowski Murine Sarcoma Virus following Passage... Immunoelectron microscopy techniques, using immunoferitin and immunoperoxidase, were applied to the study of viral envelope antigens following passage of the Soehner-Dmochowski isolate of the murine sarcoma virus in rats and hamsters. Results of this study have demonstrated that the envelope antigens of Soehner-Dmochowski murine sarcoma virus recovered from rat bone tumor cells were distinct from those of Soehner-Dmochowski murine sarcoma virus recovered from the hamster bone tumor cells. The usefulness of these immunoelectron microscopy techniques is illustrated. 1 This study was supported in part by USPHS Contract NO1-CP-33304 within the Virus Cancer Program of the National Cancer Institute, NIH, Bethesda, Md.; by Grants CA-05831 and RR-05511 from the National Cancer Institute, NIH, USPHS; and by a grant from the Leukemia Society of America, Inc. 2 To whom requests for reprints should be addressed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cancer Research American Association of Cancer Research

An Immunoelectron Microscopy Study of Soehner-Dmochowski Murine Sarcoma Virus following Passage in Rats and Hamsters

An Immunoelectron Microscopy Study of Soehner-Dmochowski Murine Sarcoma Virus following Passage in Rats and Hamsters

Cancer Research , Volume 34 (11): 2906 – Nov 1, 1974

Abstract

Immunoelectron microscopy techniques, using immunoferitin and immunoperoxidase, were applied to the study of viral envelope antigens following passage of the Soehner-Dmochowski isolate of the murine sarcoma virus in rats and hamsters. Results of this study have demonstrated that the envelope antigens of Soehner-Dmochowski murine sarcoma virus recovered from rat bone tumor cells were distinct from those of Soehner-Dmochowski murine sarcoma virus recovered from the hamster bone tumor cells. The usefulness of these immunoelectron microscopy techniques is illustrated. 1 This study was supported in part by USPHS Contract NO1-CP-33304 within the Virus Cancer Program of the National Cancer Institute, NIH, Bethesda, Md.; by Grants CA-05831 and RR-05511 from the National Cancer Institute, NIH, USPHS; and by a grant from the Leukemia Society of America, Inc. 2 To whom requests for reprints should be addressed.

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Publisher
American Association of Cancer Research
Copyright
Copyright © 1974 by the American Association for Cancer Research.
ISSN
0008-5472
Publisher site

Abstract

Immunoelectron microscopy techniques, using immunoferitin and immunoperoxidase, were applied to the study of viral envelope antigens following passage of the Soehner-Dmochowski isolate of the murine sarcoma virus in rats and hamsters. Results of this study have demonstrated that the envelope antigens of Soehner-Dmochowski murine sarcoma virus recovered from rat bone tumor cells were distinct from those of Soehner-Dmochowski murine sarcoma virus recovered from the hamster bone tumor cells. The usefulness of these immunoelectron microscopy techniques is illustrated. 1 This study was supported in part by USPHS Contract NO1-CP-33304 within the Virus Cancer Program of the National Cancer Institute, NIH, Bethesda, Md.; by Grants CA-05831 and RR-05511 from the National Cancer Institute, NIH, USPHS; and by a grant from the Leukemia Society of America, Inc. 2 To whom requests for reprints should be addressed.

Journal

Cancer ResearchAmerican Association of Cancer Research

Published: Nov 1, 1974

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