-
S.
Studenberg,
K.
Brouwer
(1992)
Impaired biliary excretion of acetaminophen glucuronide in the isolated perfused rat liver after acute phenobarbital treatment and in vivo phenobarbital pretreatment.
The Journal of pharmacology and experimental therapeutics, 261 3
-
R.
Elferink,
D.
Meijer,
F.
Kuipers,
Peter
Jansen,
A.
Groen,
G.
Groothuis
(1995)
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.
Biochimica et biophysica acta, 1241 2
-
O.
Lowry,
N.
Rosebrough,
A.
Farr,
R.
Randall
(1951)
Protein measurement with the Folin phenol reagent.
The Journal of biological chemistry, 193 1
-
M.
Soresi,
A.
Carroccio,
G.
Bonfissuto,
Vincenzo
Agate,
C.
Magliarisi,
Federico
Aragona,
Massimo
Levrero,
A.
Notarbartolo,
G.
Montalto
(1998)
Ultrasound detection of abdominal lymphadenomegaly in subjects with hepatitis C virus infection and persistently normal transaminases: a predictive index of liver histology severity.
Journal of hepatology, 28 4
-
P.
Jansen,
W.
Peters,
W.
Lamers
(1985)
Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport
Hepatology, 5
-
D.
Johnson,
C.
Klaassen
(2002)
Role of rat multidrug resistance protein 2 in plasma and biliary disposition of dibromosulfophthalein after microsomal enzyme induction.
Toxicology and applied pharmacology, 180 1
-
L.
Rausch‐Derra,
D.
Hartley,
P.
Meier,
C.
Klaassen
(2001)
Differential effects of microsomal enzyme–inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2
Hepatology, 33
-
J.
König,
D.
Rost,
Yunhai
Cui,
D.
Keppler
(1999)
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
Hepatology, 29
-
G.
Jedlitschky,
I.
Leier,
U.
Buchholz,
K.
Barnouin,
G.
Kurz,
D.
Keppler
(1996)
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.
Cancer research, 56 5
-
D.
Johnson,
S.
Habeebu,
C.
Klaassen
(2002)
Increase in bile flow and biliary excretion of glutathione-derived sulfhydryls in rats by drug-metabolizing enzyme inducers is mediated by multidrug resistance protein 2.
Toxicological sciences : an official journal of the Society of Toxicology, 66 1
-
K.
Brouwer,
H.
Kostenbauder,
P.
McNamara,
R.
Blouin
(1984)
Phenobarbital in the genetically obese Zucker rat. I. Pharmacokinetics after acute and chronic administration.
The Journal of pharmacology and experimental therapeutics, 231 3
-
T.
Kitamura,
Peter
Jansen,
C.
Hardenbrook,
Yukio
Kamimoto,
Z.
Gatmaitan,
I.
Arias
(1990)
Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia.
Proceedings of the National Academy of Sciences of the United States of America, 87 9
-
Ari
Bergwerk,
Xiaoying
Shi,
Allison
Ford,
N.
Kanai,
E.
Jacquemin,
R.
Burk,
S.
Bai,
P.
Novikoff,
Bruno
Stieger,
P.
Meier,
V.
Schuster,
A.
Wolkoff
(1996)
Immunologic distribution of an organic anion transport protein in rat liver and kidney.
The American journal of physiology, 271 2 Pt 1
-
J.
Watkins,
C.
Klaassen
(1982)
Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat.
The Journal of pharmacology and experimental therapeutics, 220 2
-
N.
Sládek,
G.
Mannering
(1969)
Induction of drug metabolism. I. Differences in the mechanisms by which polycyclic hydrocarbons and phenobarbital produce their inductive effects on microsomal N-demethylating systems.
Molecular pharmacology, 5 2
-
G.
Hong,
M.
Bazin-Redureau,
P.
Gires,
J.
Scherrmann
(1998)
Hepatic disposition and toxicity of cationized goat immunoglobulin G and fab fragments in isolated perfused rat liver.
Drug metabolism and disposition: the biological fate of chemicals, 26 7
-
H.
Xiong,
H.
Suzuki,
Y.
Sugiyama,
P.
Meier,
G.
Pollack,
K.
Brouwer
(2002)
Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment.
Drug metabolism and disposition: the biological fate of chemicals, 30 9
-
J.
König,
A.
Nies,
Yunhai
Cui,
I.
Leier,
D.
Keppler
(1999)
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
Biochimica et biophysica acta, 1461 2
-
Marcel
Kool,
M.
Linden,
M.
Haas,
G.
Scheffer,
J.
Vree,
Alexander
Smith,
G.
Jansen,
G.
Peters,
N.
Ponne,
R.
Scheper,
R.
Elferink,
F.
Baas,
P.
Borst
(1999)
MRP3, an organic anion transporter able to transport anti-cancer drugs.
Proceedings of the National Academy of Sciences of the United States of America, 96 12
-
K.
Ogawa,
H.
Suzuki,
T.
Hirohashi,
T.
Ishikawa,
P.
Meier,
K.
Hirose,
T.
Akizawa,
M.
Yoshioka,
Y.
Sugiyama
(2000)
Characterization of inducible nature of MRP3 in rat liver.
American journal of physiology. Gastrointestinal and liver physiology, 278 3
-
D.
Ortiz,
Shaohua
Li,
R.
Iyer,
Xingming
Zhang,
P.
Novikoff,
I.
Arias
(1999)
MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte.
American journal of physiology. Gastrointestinal and liver physiology, 276 6
-
(1998)
Expression of the hepatocyte canalicular multidrug resistance associated protein 2 (MRP2) in primary biliary cirrhosis (Abstract)
-
D.
Roerig,
A.
Hasegawa,
R.
Peterson,
R.
Wang
(1974)
Effect of chloroquine and phenobarbital on morphine glucuronidation and biliary excretion in the rat.
Biochemical pharmacology, 23 8
-
K.
Bock,
W.
Fröhling,
H.
Remmer,
B.
Rexer
(1973)
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.
Biochimica et biophysica acta, 327 1
-
N.
Hagenbuch,
C.
Reichel,
Bruno
Stieger,
V.
Cattori,
K.
Fattinger,
L.
Landmann,
P.
Meier,
G.
Kullak-Ublick
(2001)
Effect of phenobarbital on the expression of bile salt and organic anion transporters of rat liver.
Journal of hepatology, 34 6
-
H.
Xiong,
K.
Turner,
E.
Ward,
P.
Jansen,
K.
Brouwer
(2000)
Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats.
The Journal of pharmacology and experimental therapeutics, 295 2
-
J.
Madon,
B.
Hagenbuch,
L.
Landmann,
P.
Meier,
B.
Stieger
(2000)
Transport function and hepatocellular localization of mrp6 in rat liver.
Molecular pharmacology, 57 3
-
(1979)
Biliary and urinary excretion of phenobarbital and parahydroxyphenobarbital in rats with bile fistula
-
S.
Sher
(1971)
Drug enzyme induction and drug interactions: literature tabulation.
Toxicology and applied pharmacology, 18 4
-
M.
Trauner,
M.
Arrese,
C.
Soroka,
M.
Ananthanarayanan,
T.
Koeppel,
S.
Schlosser,
F.
Suchy,
D.
Keppler,
J.
Boyer
(1997)
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis.
Gastroenterology, 113 1
-
Z.
Gregus,
C.
Madhu,
C.
Klaassen
(1990)
Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats. Decreased hepatobiliary and increased hepatovascular transport of acetaminophen-glucuronide after microsomal enzyme induction.
Drug metabolism and disposition: the biological fate of chemicals, 18 1
-
K.
Brouwer,
J.
Jones
(1990)
Altered hepatobiliary disposition of acetaminophen metabolites after phenobarbital pretreatment and renal ligation: evidence for impaired biliary excretion and a diffusional barrier.
The Journal of pharmacology and experimental therapeutics, 252 2