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Biogenic Amines , Vol. 18, No. 1, pp. 1 – 17 (2003) Ó VSP 2003. Also available online - www.vsppub.com Veri cation of use and disuse theory of Lamarck in vertebrates using biomaterials KATSUNARI NISHIHARA ¤ President of Nishihara Institute, Hara Building 301, 6-2-5 Roppongi, Minatoku, Tokyo Received 12 April 2003; revised 10 May 2003; accepted 15 May 2003 Abstract —The material foundations moulding the vertebrate are skeletal substances, which are collagen, cartilage and bone. If any of them can be synthesized intact arti cially, the causes of chondri cation of collagen and ossi cation of cartilage that occur in the process of evolution, will be clari ed. The reason is that in the process of the evolution of this phylum, changes from collagen to cartilage and from cartilage to bone alone are observed in terms of materials. Vertebrates pose three riddles to be solved: the development of evolution, of the immune system, and of bone marrow hemopoiesis. These riddles can be investigated all at once by developing arti cial bone marrow chambers made of synthetic hydroxyapatite (HA). The development of bone marrow hemopoiesis occurs in the second revolution of evolution. The bone marrow system is the equipment
Biogenic Amines – Brill
Published: Jan 1, 2003
Keywords: ONTOGENY AND PHYLOGENY; MORPHOLOGY; ARTIFICIAL ORGAN; SKELETAL SUBSTANCE; BIOGENIC LAW; BIOMECHANICS; MOLECULAR BIOLOGY; USE AND DISUSE THEORY; EVOLUTION OF VERTEBRATES
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