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ON THE PRODUCTION OF HORMONES IN THE THYROID GLAND OF BIRDS (COCKERELS) A QUANTITATIVE STUDY WITH THE HELP OF RADIOIODINE AND ANTITHYROID DRUGS by L. VLIJM (Zoological Laboratory, Free University, Amsterdam) I. INTRODUCTION During the last i years the study of thyroid physiology has progressed greatly. This progress was due to the development of new physical and chemical techniques, for instance the application of radioiodine (mostly in thyroid studies 1131 is used), of antithyroid drugs, and of paperchro- matographical and radioautographical techniques. With the aid of these expedients our knowledge about the biosynthesis of hormones in the thyroid gland advanced greatly. In surveying the literature on the thyroid there is a striking prepon- derance of investigations with mammals as experimental animals, whereas only incidentally attention has been drawn to other classes of the vertebrates. Next it is clear that there have been only few investigations giving a quantitative account of the processes inside the thyroid gland. Studies are mostly either qualitative, or they inform about the quantitative release of hormones by the thyroid gland, without going into the syn- thesis of hormones within the thyroid gland. We have tried to investigate the biosynthesis of thyroid hormones in birds,
Archives Néerlandaises de Zoologie (in 1967 continued as Netherlands Journal of Zoology) – Brill
Published: Jan 1, 1958
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