Toxicology Mechanisms and Methods Volume 16 Issue 8

Journal Article

A Physiological Pharmacokinetic Model Based on Tissue Lipid Content for Simulating Inhalation Pharmacokinetics of Highly Lipophilic Volatile Organic Chemicals

Emond, Claude; Krishnan, Kannan

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376510600860474 pmid:20021013

The highly lipophilic volatile organic chemicals (HLVOCs) are distributed almost uniquely in the neutral lipid fraction of tissues and blood. As suggested by their high n-octanol:water partition coefficient (>1000), their solubility in water fraction of tissues and blood is negligible....

Download Only

Journal Article

Deaths Due to Corrosive Ingestion: A 10-Year Retrospective Study

Kar, Hakan; Batuk, Gokhan; Cekin, Necmi; Isler, Hulya Batuk; Uzun, Ibrahim;

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376510600860490 pmid:20021014

Objectives: Evaluation of the substances used, macroscopic and microscopic autopsy findings, and the manner of corrosive ingestion deaths in Istanbul are aimed in this study. Methods: The autopsy records of the corrosive ingestion cases in Istanbul, Turkey, between 1992 and 2001 are investigated...

Download Only

Journal Article

Development of Functional Fish Feed with Natural Ingredients to Control Heavy Metals

Jia, Huijun; Ren, Huifeng; Maita, Masashi; Satoh, Shuichi; Endo, Hideaki;

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600666995 pmid:20021015

The effects of two natural ingredients, Chinese parsley (CP) and chitosan (CT), on growth, accumulation, and excretion of cadmium in fish body and preservation of essential trace metals in the body were investigated by using rainbow trout that had been fed cadmium-added diet, low and high...

Download Only

Journal Article

Myofibril Membranes in Relation to the Neuromuscular Weakness of Acute Monocrotophos Poisoning

Venkatesh, Selvaraj; Zachariah, Anand; Oommen, Anna

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600685813 pmid:20021016

Organophosphate poisoning is a common method of deliberate self-harm in countries where the pesticides are readily available. The severity of neuroparalysis and myopathy occurring in acute organophosphate poisoned patients is determined by the severity of poisoning and is associated with...

Download Only

Journal Article

Comparison of Elisa- and LC-MS-Based Methodologies for the Exposure Assessment of Bisphenol A

Fukata, Hideki; Miyagawa, Hidenori; Yamazaki, Noriko; Mori, Chisato

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600697404 pmid:20021017

Several types of methods, mainly liquid chromatography (LC), have been used for the analysis and assessment of bisphenol A (BPA) in human biological samples. Enzyme-linked immunosorbent assay (ELISA) is also being used for BPA measurement. In this study, we verified whether ELISA is suitable for...

Download Only

Journal Article

In Vitro Test-Based Comparison of Pesticide-Induced Sensitivity in Marine and Freshwater Phytoplankton

Arzul, Geneviève; Quiniou, Françoise; Carrie, Cécile

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600698717 pmid:20021018

This study aims to assess the effects of two pesticides, namely the insecticide carbofuran and the herbicide isoproturon, on monospecifically cultivated marine and freshwater phytoplankton according to standard methods. In the presence of pesticide, growth rates were lower in marine species...

Download Only

Journal Article

Safety Assessment of a Novel Niacin-Bound Chromium-Based Energy Formulation

Shara, M. A.; Yasmin, T.; Chatterjee, A.; Bagchi, M.; Maulik, N.;

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600709746 pmid:20021019

Over 35 million adults suffer from fatigue or lack of energy. In this study, we assessed the safety of a novel niacin-bound chromium-based Energy Formulation, which also contained caffeine, D-ribose, Withania somnifera extract, and selected amino acids. Niacin-bound chromium is a novel source of...

Download Only

Journal Article

Effect of Four Organophosphorus Compounds on Human Blood Acetylcholinesterase: In Vitro Studies

Das, G. Prabhavathy; Jamil, Kaiser; Rahman, M. F.

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600719281 pmid:20021020

In the present investigation acetylcholinesterase (AChE) was estimated in erythrocytes from blood samples exposed to four commonly used organophosphorus pesticides in vitro. The aim of the study was to determine the IC50 concentration of the pesticides monocrotophos, chlorpyrifos, profenofos, and...

Download Only

Journal Article

Hypolipidemic Effect of Ginger in 1,2-Dimethyl Hydrazine-Induced Experimental Colon Carcinogenesis

Manju, V.; Viswanathan, P.; Nalini, N.

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600728811 pmid:20021021

Colorectal cancer is increasingly common nowadays in Asian countries and still remains the second leading cause of cancer death in the United States. In our laboratory, we studied the chemopreventive and hypolipidemic effect of ginger, a dietary spice, in 1,2-dimethylhydrazine (DMH)-induced colon...

Download Only

Journal Article

LHRH-PE40-Induced Vascular Leak Syndrome

Li, Jun; Zhang, Jin-kun

2006 Toxicology Mechanisms & Methods

doi:10.1080/15376520600735196 pmid:20021022

Aim: This study was designed to study the toxicity of LHRH-PE40, a recombinant DNA-derived protein composed of the decapeptide known as luteinizing hormone-releasing hormone and the translocation and catalytic domains of pseudomonas exotoxin A. Method: Single-dose and repeat-dose toxicity of...

Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Toxicology Mechanisms and Methods Volume 16 Issue 8

Related Journals:

Advanced Search

Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Toxicology Mechanisms and Methods Volume 16 Issue 8

Related Journals:

Our policy towards the use of cookies