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Drug Metabolism and Disposition Volume 36 Issue 4

2013
- Volume 41
  - Issue 2 (Feb)
  - Issue 1 (Jan)
2012
- Volume 40
2011
- Volume 39
2010
- Volume 38
2009
- Volume 37
2008
- Volume 36
2007
- Volume 35
2006
- Volume 34
2005
- Volume 33
2004
- Volume 32
2003
- Volume 31
2002
- Volume 30
2001
- Volume 29
2000
- Volume 28
1999
- Volume 27
1998
- Volume 26
1997
- Volume 25

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Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho1,2-bpyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals

Savage, Ronald E.; Tyler, Andrew N.; Miao, Xiu-Sheng; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 753 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide

Ishiguro, Naoki; Maeda, Kazuya; Saito, Asami; Kishimoto, Wataru; Matsushima, Soichiro; Ebner, Thomas; Roth, Willy; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 796 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats

Li, Chunze; Grillo, Mark P.; Badagnani, Ilaria; Fife, Kimberly L.; Benet, Leslie Z.

Follow Drug Metabolism and Disposition , Volume 36 (4): 682 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol1,2-bpyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood

Miao, Xiu-Sheng; Song, Pengfei; Savage, Ronald E.; Zhong, Caiyun; Yang, Rui-Yang; Kizer, Darin; Wu, Hui; Volckova, Erika; Ashwell, Mark A.; Supko, Jeffrey G.; He, Xiaoying; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 641 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)

Zimmermann, Christian; van de Wetering, Koen; van de Steeg, Evita; Wagenaar, Els; Vens, Conchita; Schinkel, Alfred H.

Follow Drug Metabolism and Disposition , Volume 36 (4): 631 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-(3-fluorobenzyl)oxyphenyl}-6-5-({2-(methylsulfonyl)ethylamino}methyl)-2-furyl-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions

Polli, Joseph W.; Humphreys, Joan E.; Harmon, Kelly A.; Castellino, Stephen; O'Mara, Michael J.; Olson, Katie L.; John-Williams, Lisa St.; Koch, Kevin M.; Serabjit-Singh, Cosette J.

Follow Drug Metabolism and Disposition , Volume 36 (4): 695 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury

Matsuzaki, Takanobu; Morisaki, Takafumi; Sugimoto, Wakako; Yokoo, Koji; Sato, Daisuke; Nonoguchi, Hiroshi; Tomita, Kimio; Terada, Tomohiro; Inui, Ken-ichi; Hamada, Akinobu; Saito, Hideyuki

Follow Drug Metabolism and Disposition , Volume 36 (4): 649 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro

Richert, Lysiane; Tuschl, Gregor; Viollon-Abadie, Catherine; Blanchard, Nadège; Bonet, Alexandre; Heyd, Bruno; Halkic, Nermin; Wimmer, Elmar; Dolgos, Hugues; Mueller, Stefan O.

Follow Drug Metabolism and Disposition , Volume 36 (4): 702 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans

Matsushima, Soichiro; Maeda, Kazuya; Ishiguro, Naoki; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 663 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008
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Metabolite Generation via Microbial Biotransformations with Actinomycetes: Rapid Screening for Active Strains and Biosynthesis of Important Human Metabolites of Two Development-Stage Compounds, 5-(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro4.4non7-yl-methyl-3-thiophenecarboxylic Acid (BMS-587101) and Dasatinib

Li, Wenying; Josephs, Jonathan L.; Skiles, Gary L.; Humphreys, W. Griffith

Follow Drug Metabolism and Disposition , Volume 36 (4): 721 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Drug Metabolism and Disposition Volume 36 Issue 4

Identification of a Novel Glucosylsulfate Conjugate as a Metabolite of 3,4-Dihydro-2,2-dimethyl-2H-naphtho1,2-bpyran-5,6-dione (ARQ 501, β-Lapachone) in Mammals

Savage, Ronald E.; Tyler, Andrew N.; Miao, Xiu-Sheng; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 753 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Establishment of a Set of Double Transfectants Coexpressing Organic Anion Transporting Polypeptide 1B3 and Hepatic Efflux Transporters for the Characterization of the Hepatobiliary Transport of Telmisartan Acylglucuronide

Ishiguro, Naoki; Maeda, Kazuya; Saito, Asami; Kishimoto, Wataru; Matsushima, Soichiro; Ebner, Thomas; Roth, Willy; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 796 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Differential Effects of Fibrates on the Metabolic Activation of 2-Phenylpropionic Acid in Rats

Li, Chunze; Grillo, Mark P.; Badagnani, Ilaria; Fife, Kimberly L.; Benet, Leslie Z.

Follow Drug Metabolism and Disposition , Volume 36 (4): 682 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Identification of the in Vitro Metabolites of 3,4-Dihydro-2,2-dimethyl-2H-naphthol1,2-bpyran-5,6-dione (ARQ 501; β-Lapachone) in Whole Blood

Miao, Xiu-Sheng; Song, Pengfei; Savage, Ronald E.; Zhong, Caiyun; Yang, Rui-Yang; Kizer, Darin; Wu, Hui; Volckova, Erika; Ashwell, Mark A.; Supko, Jeffrey G.; He, Xiaoying; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 641 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Species-Dependent Transport and Modulation Properties of Human and Mouse Multidrug Resistance Protein 2 (MRP2/Mrp2, ABCC2/Abcc2)

Zimmermann, Christian; van de Wetering, Koen; van de Steeg, Evita; Wagenaar, Els; Vens, Conchita; Schinkel, Alfred H.

Follow Drug Metabolism and Disposition , Volume 36 (4): 631 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

The Role of Efflux and Uptake Transporters in N-{3-Chloro-4-(3-fluorobenzyl)oxyphenyl}-6-5-({2-(methylsulfonyl)ethylamino}methyl)-2-furyl-4-quinazolinamine (GW572016, Lapatinib) Disposition and Drug Interactions

Polli, Joseph W.; Humphreys, Joan E.; Harmon, Kelly A.; Castellino, Stephen; O'Mara, Michael J.; Olson, Katie L.; John-Williams, Lisa St.; Koch, Kevin M.; Serabjit-Singh, Cosette J.

Follow Drug Metabolism and Disposition , Volume 36 (4): 695 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Altered Pharmacokinetics of Cationic Drugs Caused by Down-Regulation of Renal Rat Organic Cation Transporter 2 (Slc22a2) and Rat Multidrug and Toxin Extrusion 1 (Slc47a1) in Ischemia/Reperfusion-Induced Acute Kidney Injury

Matsuzaki, Takanobu; Morisaki, Takafumi; Sugimoto, Wakako; Yokoo, Koji; Sato, Daisuke; Nonoguchi, Hiroshi; Tomita, Kimio; Terada, Tomohiro; Inui, Ken-ichi; Hamada, Akinobu; Saito, Hideyuki

Follow Drug Metabolism and Disposition , Volume 36 (4): 649 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Species Differences in the Response of Liver Drug-Metabolizing Enzymes to (S)-4-O-Tolylsulfanyl-2-(4-trifluormethyl-phenoxy)-butyric Acid (EMD 392949) in Vivo and in Vitro

Richert, Lysiane; Tuschl, Gregor; Viollon-Abadie, Catherine; Blanchard, Nadège; Bonet, Alexandre; Heyd, Bruno; Halkic, Nermin; Wimmer, Elmar; Dolgos, Hugues; Mueller, Stefan O.

Follow Drug Metabolism and Disposition , Volume 36 (4): 702 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Investigation of the Inhibitory Effects of Various Drugs on the Hepatic Uptake of Fexofenadine in Humans

Matsushima, Soichiro; Maeda, Kazuya; Ishiguro, Naoki; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 663 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Li, Wenying; Josephs, Jonathan L.; Skiles, Gary L.; Humphreys, W. Griffith

Follow Drug Metabolism and Disposition , Volume 36 (4): 721 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

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Drug Metabolism and Disposition Volume 36 Issue 4

1 - 10 of 22 articles

Savage, Ronald E.; Tyler, Andrew N.; Miao, Xiu-Sheng; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 753 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Ishiguro, Naoki; Maeda, Kazuya; Saito, Asami; Kishimoto, Wataru; Matsushima, Soichiro; Ebner, Thomas; Roth, Willy; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 796 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Li, Chunze; Grillo, Mark P.; Badagnani, Ilaria; Fife, Kimberly L.; Benet, Leslie Z.

Follow Drug Metabolism and Disposition , Volume 36 (4): 682 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Miao, Xiu-Sheng; Song, Pengfei; Savage, Ronald E.; Zhong, Caiyun; Yang, Rui-Yang; Kizer, Darin; Wu, Hui; Volckova, Erika; Ashwell, Mark A.; Supko, Jeffrey G.; He, Xiaoying; Chan, Thomas C. K.

Follow Drug Metabolism and Disposition , Volume 36 (4): 641 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Zimmermann, Christian; van de Wetering, Koen; van de Steeg, Evita; Wagenaar, Els; Vens, Conchita; Schinkel, Alfred H.

Follow Drug Metabolism and Disposition , Volume 36 (4): 631 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Polli, Joseph W.; Humphreys, Joan E.; Harmon, Kelly A.; Castellino, Stephen; O'Mara, Michael J.; Olson, Katie L.; John-Williams, Lisa St.; Koch, Kevin M.; Serabjit-Singh, Cosette J.

Follow Drug Metabolism and Disposition , Volume 36 (4): 695 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Matsuzaki, Takanobu; Morisaki, Takafumi; Sugimoto, Wakako; Yokoo, Koji; Sato, Daisuke; Nonoguchi, Hiroshi; Tomita, Kimio; Terada, Tomohiro; Inui, Ken-ichi; Hamada, Akinobu; Saito, Hideyuki

Follow Drug Metabolism and Disposition , Volume 36 (4): 649 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Richert, Lysiane; Tuschl, Gregor; Viollon-Abadie, Catherine; Blanchard, Nadège; Bonet, Alexandre; Heyd, Bruno; Halkic, Nermin; Wimmer, Elmar; Dolgos, Hugues; Mueller, Stefan O.

Follow Drug Metabolism and Disposition , Volume 36 (4): 702 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Matsushima, Soichiro; Maeda, Kazuya; Ishiguro, Naoki; Igarashi, Takashi; Sugiyama, Yuichi

Follow Drug Metabolism and Disposition , Volume 36 (4): 663 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008

Li, Wenying; Josephs, Jonathan L.; Skiles, Gary L.; Humphreys, W. Griffith

Follow Drug Metabolism and Disposition , Volume 36 (4): 721 Am. Soc for Pharma & Experimental Therapeutics – Apr 1, 2008